Browse > Article

Effects of In Vitro Synergism of Eunkyo-san and Rufloxacin against 9 Strains of Aerobic Gram(+) Bacteria  

Shin Ho Pill (Division of Respiratory System, College of Oriental Medicine, Daegu Haany University)
Jeon Kwi Ok (Division of Respiratory System, College of Oriental Medicine, Daegu Haany University)
Park Mee Yeon (Division of Respiratory System, College of Oriental Medicine, Daegu Haany University)
Kim Dae Jun (Division of Respiratory System, College of Oriental Medicine, Daegu Haany University)
Choi Hae Yun (Division of Respiratory System, College of Oriental Medicine, Daegu Haany University)
Kim Jong Dae (Division of Respiratory System, College of Oriental Medicine, Daegu Haany University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.18, no.6, 2004 , pp. 1740-1745 More about this Journal
Abstract
In order to evaluate the in vitro synergic effect of Eunkyo-san, with quinolone antibiotics, rufloxacin (RUFX), the minimal inhibitory concentration (MIC), MIC50 and MIC90 of single use of quinolones and concomitant treatment with Eunkyo-san against 9 strains of aerobic gram positive bacteria. The obtained results were as follows : In the case of aerobic gram positive bacteria, the MIC, MIC50 and MIC90 against Staphylococcus aureus, Staphylococcus aureus smith, Staphylococcus epidermidis, Staphylococcus pyogens, Streptococcus pneumoniae Type Ⅰ, Type Ⅱ and Type Ⅲ was significantly decreased in concomitant treated groups with Eunkyo-san compared to those of single treated groups of RUFX, respectively. However, no significant changes were demonstrated against Bacillus subtilis and Enterococcus faecalis. In conclusion, the in vitro antibacterial activity of RUFX were increased against some strains of aerobic gram positive strains, especially, pneumococcus such as Staphylococcus and Streptococcus by concomitant use of Eunkyo-san.
Keywords
Rufloxacin(RUFX); Eunkyo-san(銀翹散); Aerobic gram positive bacteria;
Citations & Related Records
연도 인용수 순위
  • Reference
1 In vitro short-term and long-term cytotoxicity of fluoroquinolones on murine cell lines /
[ Pessina A;Gribaldo L;Mineo E;Neri MG ] / Indian J Exp Biol
2 /
[ 정희영 ] / 항생제의 길잡이
3 Clinical use of the quinolones /
[ Neu HC ] / Lancet
4 Antibiotic resistance /
[ Cunha BA ] / Med Clin North Am
5 Single or double mutation alterations of gyrA associated with fluoroquinolone resistance in Campylobacter jejuni and Campylobacter coli /
[ Bachoual R;Ouabdesselam S;Mory F;Lascols C;Soussy CJ;Tankovic J. ] / Microb Drug Resist   ScienceOn
6 A sequence variant of Staphylococcus hominis with a high prevalence of oxacillin and fluoroquinolone resistance /
[ Fitzgibbon JE;Nahvi MD;Dubin DT;John JF Jr. ] / Res Microbiol
7 Reduced fluoroquinolone susceptibility in Salmonella enterica serotypes in travelers returning from southeast Asia /
[ Hakanen A;Kotilainen P;Huovinen P;Helenius H;Siitonen A. ] / Emerg Infect Dis
8 New mutation in parE in a pneumococcal in vitro mutant resistant to fluoroquinolones /
[ Janoir C;Varon E;Kitzis MD;Gutmann L. ] / Antimicrob Agents Chemother
9 Characterization of sparfloxacin-resistant mutants of Staphylococcus aureus obtained in vitro /
[ Ruiz J;Sierra JM;De Anta MT;Vila J. ] / Int J Antimicrob Agents
10 Fluoroquinolone resistance among clinical isolates of Streptococcus pneumoniae belonging to international multiresistant clones /
[ McGee L;Goldsmith CE;Klugman KP. ] / J Antinicrob Chemother
11 麻黃潤肺湯이 ovalbumin으로 誘發된 mouse의 喘息에 미치는 影響 /
[ 감철우 ] / 대구한의대학교대학원 박사학위논문
12 麻黃潤肺湯과 rufloxacin 倂用이 Gram(+) 細菌柱에 대한 試驗管內 抗菌力에 미치는 影響 /
[ 박미연 ] / 대구한의대학교대학원 석사학위논문
13 麻黃潤肺湯과 ciproxacin 倂用이 Gram(+) 細菌柱에 대한 試驗管內 抗菌力에 미치는 影響 /
[ 金大俊;金鍾大 ] / 대한본초학회지
14 A new tricyclic fluoroquinolone, rufloxacin(MF-934), with interesting antibacterial and pharmacokinetic characteristics /
[ Segre G;Cerretani D;Cerri D;Moltoni L. ] / Drugs Exp Clin Res
15 In vitro activity of a new quinolone, rufloxacin, against nosocomial isolates /
[ Mattina R;Cocuzza CE;Cesana M;Bonfiglio G. ] / Chemotherapy
16 Fluoroquinolones: utilization in renal and urogenital tract infections /
[ Farker K;Naber KG;Funfstuck R. ] / Med Klin
17 /
[ 楊進(編) ] / 溫病條辨
18 /
[ 김상찬;김선희(외 9명) ] / 방제학
19 Quinolone generations: natural history or natural selection? /
[ Ball P ] / J Antimicrob Chemother.
20 Is more than one quinolone needed in clinical practice? /
[ Paladino JA ] / Ann. Pharmacother
21 Mode of action of fluoroquinolones /
[ Hooper DC ] / Drugs
22 Mechanisms of action of antimicrobials: focus on fluoroquinolones /
[ Hooper DC ] / Drugs
23 History of quinolones and their side effects /
[ Rubinstein E ] / Chemotherapy
24 Toxicity of quinolones /
[ Stahlmann R.;Lode H. ] / Drugs
25 Rufloxacin(MF-934): in vitro and in vivo antibacterial activity /
[ Ravizzola G;Pinsi G;Pirali F;Colombrita D;Foresti I;Peroni L;Turano A. ] / Drugs Exp Clin Res