Pediatric Infection and Vaccine

The Korean Society of Pediatric Infectious Diseases (대한소아감염학회)
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A Case of Subacute Necrotizing Lymphadenitis Associated with Yersinia Infection in a 12 Years Old Child

소아에서 발생한 Yersinia pseudotuberculosis 감염이 동반된 아급성 괴사성 림프절염 1례

  • Sim, Yoon-Hee (Departments of Pediatrics, College of Medicine, Chung Ang University) ;
  • Lim, In Seok (Departments of Pediatrics, College of Medicine, Chung Ang University) ;
  • Lee, Dong Keun (Departments of Pediatrics, College of Medicine, Chung Ang University)
  • 심윤희 (중앙대학교 의과대학 소아과학교실) ;
  • 임인석 (중앙대학교 의과대학 소아과학교실) ;
  • 이동근 (중앙대학교 의과대학 소아과학교실)
  • Published : 2003.05.31
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Abstract

Kikuchi disease(subacute necrotizing lymphadenitis), first reported by Kikuchi and Fujimoto in 1972, is a benign self-limiting illness characterized by fever, neutropenia and cervical lymphadenopathy and develops predominantly in young women, especially in Asia. The cause of Kikuchi disease is unknown, but postinfectious(virus or bacteria) hyperimmune reaction has been suggested. Few pediatric cases have been reported. We experienced a case of Kikuchi disease associated with Yersinia pseudotuberculosis infection in 12-year-old girl. After she was admitted with cervical lymphadenopathy and headache, followed by sustained fever with leukopenia. All symptoms and signs did not seem to be responded to antimicobial treatment. Open biopsy of cervical lymph node was performed and showed findings consistent with subacute necrotizing lymphadenitis. Serologic studies were all negative except for Y. pseudotuberculosis. Fever subsided and lymphadenopathy improved after administration of oral steroid for 1 week.

저자들은 내원 10일 전부터 발현된 경부 종괴를 주소로 내원한 12세 여아에서 혈청학적 검사상 증명된 Yersinia 감염을 동반한 아급성 괴사성 림프절염 1례를 경험하였기에 이를 문헌고찰과 함께 보고하는 바이다.

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