약학회지 (YAKHAK HOEJI)

  • 제47권5호
  • /
  • Pages.283-287
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  • 2003
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  • 0377-9556(pISSN)
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  • 2383-9457(eISSN)
대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

퀴놀론 계열 이소플라보노이드의 합성

Synthesis of Quinolone Analogs of Isoflavonoids

  • 전라옥 (숙명여자대학교 약학대학) ;
  • 이지혜 (숙명여자대학교 약학대학) ;
  • 정상헌 (충남대학교 약학대학)
  • 발행 : 2003.10.01
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초록

Isoflavonoids are abundant in natural products and reported with many synthetic variations. However, relatively few quinolone analogs of isoflavonoids have been described. As part of our endeavor to pursue biologically active novel isoflavonoids, we report an efficient synthetic route for quinolone analogs of isoflavonoids. The key intermediate, 2'-aminochalcone 2 was obtained from substituted aniline and cyclized to afford quinolones 6, 8a, and 8b.

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참고문헌

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