Abstract
The fractions extracted with methylene chloride from colored rice seeds of 19 cultivars were prepared to examine the correlationties of both antimutagenicity and antioxidiativity with physiological functionalities. The data revealed a positive correlation of the antimutagenicity with the content of $(3.{\beta},22Z)-Acetate-stigmasta-5,22-dien-3-ol$, 24-Oxocholesterol acetate, 6(E),8(E)-Heptadiene, and Eicosane. For antioxidativity, electron donating ability to DPPH radicals exhibited a positive correlation with the content of (24R,25S)-Aplysterylacetate, however, negative correlations were found between scavenging activity toward hydroxyl radicals and the content of either Tetradecanoic acid or Methyl ester-hexadecanoic acid, $(3.{\beta},24S)-Stigmast-5-en-3-ol$, respectively. In addition, a positive correlation was detected between the inhibitory effect of the fractions and the content of $(3.{\beta},24S)-Stigmast-5-en-3-ol$, however, a negative correlation with the content of 3',3'-Dimethylspiro [acridane-9,1'-indane], $(3.{\beta})-24-Methylene-9,19-cyclolanostan-3-ol$, and some other compounds was observed, respectively.
유색미 19품종에서 염화메틸렌으로 추출한 각 성분들의 항변이원성 및 항산화 효과간의 상관성을 검토하였다. 항변이원성은 $(3.{\beta},22Z)-acetate-stigmasta-5,22-dien-3-ol$, 24-oxocholesterol acetate, 6E,8(E)-heptadiene 및 eicosane의 함량과 정의 상관성이 있었다. 항산화 효과 중 DPPH radical에 대한 전자공여능은 (24R,25S)-aplysterylacetate의 함량과 정의 상관성이 있었고, hydroxy radical 소거활성은 tetradecanoic acid 및 methyl ester-hexadecanoic acid, $(3.{\beta},24S)-stigmast-5-en-3-ol$ 들의 함량과는 각각 부의 상관성이 있었다. 또한 지질과산화 억제효과는 $(3.{\beta},24S)-stigmast-5-en-3-ol$ 함량과는 정의 상관을 그리고 3',3'-dimethylspiro [acridane-9,1'-indane] 및 $(3.{\beta})-24-methylene-9,19-cyclolanostan-3-ol$ 등의 함량과는 부의 상관성이 있었다.
