Journal of the Korean Society of Food Culture (한국식생활문화학회지)

Korean Society of Food Culture (한국식생활문화학회)
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Effect of Polyphenol Compounds from Korean Pear on Immunofunctional Activity

한국산 배의 Polyphenol 화합물군이 쥐의 면역기능에 미치는 영향

  • Choi, Hee-Jin (Department of Food Science and Technology, Yeungnam University) ;
  • Han, Ho-Suk (Department of Food Science and Technology, Yeungnam University) ;
  • Park, Jung-Hye (Department of Food Science and Technology, Yeungnam University) ;
  • Bae, Jong-Ho (Department of Confectionary Decoration, Daegu Mirae College) ;
  • Woo, Hee-Seob (School of Food science, Dongju College) ;
  • An, Bong-Jeun (Faculty of Life Resources and Engineering, Kyungsan University) ;
  • Bae, Man-Jong (Faculty of Life Resources and Engineering, Kyungsan University) ;
  • Kim, Hyun-Gu (Korea Food Research Institute) ;
  • Choi, Cheong (Department of Food Science and Technology, Yeungnam University)
  • 최희진 (영남대학교 생물산업공학부) ;
  • 한호석 (영남대학교 생물산업공학부) ;
  • 박정혜 (영남대학교 생물산업공학부) ;
  • 배종호 (대구 미래대학 제과데코레이션과) ;
  • 우희섭 (동주대학 식품과학계열) ;
  • 안봉전 (경산대학교 생명자원공학부) ;
  • 배만종 (경산대학교 생명자원공학부) ;
  • 김현구 (한국식품개발연구원) ;
  • 최청 (영남대학교 생물산업공학부)
  • Published : 2003.08.30
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Abstract

This study was conducted to investigate immunofunctional activity of the polyphenol fractions isolated from Korean pear. In the experimental of Rosette forming cell, the results showed that all the polyphenol fractions enhance the cell count compared with the control group. Especially polyphenol fraction II and III showed highly significant effect on Rosette forming cell, and allergy inhibition. After antigen challenge, histamine content of blood of the polyphenol groups was lowered to near the normal group.

한국산 배로부터 polyphenol 화합물을 분리하여, 기능성 식품으로서의 근거를 제시하고자, 면역기능의 활성화에 관하여 동물실험을 하였다. 배의 polyphenol 화합물이 면역기능에 미치는 영향에 관한 실험에서는 배로부터 분리된 polyphenol 화합물 I, II 및 III에 대하여 Rosette 형성은 배의 polyphenol 화합물 II와 III을 투여한 군에서 분리된 비장과 복강 상재성 마크로파지에서 Rosette 형성능이 높은 것으로 나타났다. 항원 투여 후 혈중의 히스타민을 측정한 결과는 거의 정상군에 가깝게 혈중 histamine 함량을 낮추는 역할을 하였다.

Keywords

References

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