Endoscopic Laser Surgery in Laryngeal Carcinoma

후두 악성종양에 대한 내시경적 레이저 수술의 적용

  • Kim Kwang-Hyun (Department of Otolaryngology-Head and Neck Surgery, Seoul National University College of Medicine) ;
  • Sung Myung-Whun (Department of Otolaryngology-Head and Neck Surgery, Seoul National University College of Medicine) ;
  • Lee Hyo-Jeong (Department of Otolaryngology-Head and Neck Surgery, Seoul National University College of Medicine) ;
  • Lee Dong-Wook (Department of Otolaryngology-Head and Neck Surgery, Chungbuk University College of Medicine) ;
  • Park Bum-Jung (Department of Otolaryngology-Head and Neck Surgery, Hallym University College of Medicine) ;
  • Seong Weon-Jin (Department of Otolaryngology-Head and Neck Surgery, Inje University, Sang Gye Paik Hospital) ;
  • Min Yang-Gi (Department of Otolaryngology-Head and Neck Surgery, Seoul National University College of Medicine) ;
  • Lee Chul-Hee (Department of Otolaryngology-Head and Neck Surgery, Seoul National University College of Medicine) ;
  • Rhee Chae-Seo (Department of Otolaryngology-Head and Neck Surgery, Seoul National University College of Medicine) ;
  • Lee Sang-Jun (Department of Otolaryngology-Head and Neck Surgery, Seoul National University College of Medicine) ;
  • Roh Jong-Lyel (Department of Otolaryngology-Head and Neck Surgery, Seoul National University College of Medicine)
  • 김광현 (서울대학교 의과대학 이비인후과학교실) ;
  • 성명훈 (서울대학교 의과대학 이비인후과학교실) ;
  • 이효정 (서울대학교 의과대학 이비인후과학교실) ;
  • 이동욱 (충북대학교 의과대학 이비인후과학교실) ;
  • 박범정 (한림대학교 의과대학 이비인후과학교실) ;
  • 성원진 (인제대학교 의과대학 상계백병원 이비인후과학교실) ;
  • 민양기 (서울대학교 의과대학 이비인후과학교실) ;
  • 이철희 (서울대학교 의과대학 이비인후과학교실) ;
  • 이재서 (서울대학교 의과대학 이비인후과학교실) ;
  • 이상준 (서울대학교 의과대학 이비인후과학교실) ;
  • 노종열 (서울대학교 의과대학 이비인후과학교실)
  • Published : 2002.05.01

Abstract

Background and Objectives: To determine if laser endoscopic microsurgery is a reliable and appropriate approach in the treatment of laryngeal carcinomas. Materials and Methods: Retrospective study of 62 patients treated with CO2 laser from June 1988 to November 2000 at Seoul National University Hospital for laryngeal squamous cell carcinoma. All patients were treated with curative intention. Fifty three untreated patients with laryngeal carcinoma (39 glottic and 14 supraglottic carcinoma patients) had primary carbon dioxide laser microsurgery. Nine radiation failure patients were treated. Postoperative radiotheray was done for 17 patients. Neck dissection was performed simultaneously for 4 supraglottic cases with cervical nodal metastasis. Mean follow-up duration was 40 months. Results: In primary laser surgery group, distribution of tumors (American Joint Committee on Cancer, 1997) were 38 cases with Tl, 13 cases with T2, 2 cases with T3. Cure rate was 88.7%(47/53) and local control rate was 92.5%(49/53). Larynx was preserved in 94%(50/53) of patients. The overall 5-year survival rate(Kaplan-Meier) was 81.5%. In radiation failure group, 56% of patients were recurred after laser surgery. Conclusion: Laser surgery could be a better treatment modality for early laryngeal cancers and selected advanced cases. Additional radiation therapy should be considered if resection margin is not satisfactory.

Keywords

References

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