Clinical and Experimental Pediatrics

The Korean Pediatric Society (대한소아청소년과학회)
권호 표지

A Case of Stevens-Johnson Syndrome Plus Vanishing Bile Duct Syndrome Associated with Ibuprofen Use

Stevens-Johnson Syndrome 환아에서 발생한 Ibuprofen과 연관된 Vanishing Bile Duct Syndrome 1례

  • Choi, Jee Yee (Department of Pediatrics, Wallace Memorial Baptist Hospital) ;
  • Kim, Su Young (Department of Pediatrics, Wallace Memorial Baptist Hospital) ;
  • Byun, Soon Ok (Department of Pediatrics, Wallace Memorial Baptist Hospital) ;
  • Park, Jae Hong (Department of Pediatrics, College of Medicine, Pusan University)
  • 최지이 (부산 왈레스 기념 침례병원 소아과) ;
  • 김수영 (부산 왈레스 기념 침례병원 소아과) ;
  • 변순옥 (부산 왈레스 기념 침례병원 소아과) ;
  • 박재홍 (부산대학교 의과대학 소아과학교실)
  • Received : 2002.03.23
  • Accepted : 2002.06.11
  • Published : 2002.09.15
Download PDF
⟨ Previous Next ⟩

Abstract

Acute vanishing bile syndrome is a cause of progressive cholestasis. It is most often drug or toxin related. It's pathogenesis is unknown. Stevens-Johnson syndorme is a well-recognized immune complex-mediated hypersensitivity reaction. It is induced by drug or infection. It has classic systemic, mucosal, and dermatologic manifestations. We report a case of a 14 years old female suffering from Stevens-Johnson syndrome plus vanishing bile duct syndrome associated with ibuprofen use. We report the case with a brief review of its related literature.

저자들은 전신에 홍반성 반구진성발진과 발열을 주소로 내원한 ibuprofen을 복용한 14세 여자 환아에서 SJS, VBDS가 동반된 1례를 경험하였기에 문헌 고찰과 함께 보고한다.

Keywords