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A Case of Stevens-Johnson Syndrome Plus Vanishing Bile Duct Syndrome Associated with Ibuprofen Use  

Choi, Jee Yee (Department of Pediatrics, Wallace Memorial Baptist Hospital)
Kim, Su Young (Department of Pediatrics, Wallace Memorial Baptist Hospital)
Byun, Soon Ok (Department of Pediatrics, Wallace Memorial Baptist Hospital)
Park, Jae Hong (Department of Pediatrics, College of Medicine, Pusan University)
Publication Information
Clinical and Experimental Pediatrics / v.45, no.9, 2002 , pp. 1146-1149 More about this Journal
Abstract
Acute vanishing bile syndrome is a cause of progressive cholestasis. It is most often drug or toxin related. It's pathogenesis is unknown. Stevens-Johnson syndorme is a well-recognized immune complex-mediated hypersensitivity reaction. It is induced by drug or infection. It has classic systemic, mucosal, and dermatologic manifestations. We report a case of a 14 years old female suffering from Stevens-Johnson syndrome plus vanishing bile duct syndrome associated with ibuprofen use. We report the case with a brief review of its related literature.
Keywords
Vanishing bile duct syndorme; Stevens-Johnson syndrome; Ibuprofen;
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