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- 식품저장학 윤정의
Herbal Formula Science (대한한의학방제학회지)
- Volume 10 Issue 1
- /
- Pages.73-80
- /
- 2002
- /
- 1229-1218(pISSN)
- /
- 2288-5641(eISSN)
Purgative Effect of Jechun-Jun(Jichuan-Jian) and Add or Omit Herbs in Rat
제천전(濟川煎)과 약물(藥物) 가감(加減)이 흰쥐의 사하작용(瀉下作用)에 미치는 영향(影響)
- Lee Seung-Hee (Seoul Perfumery Research institute) ;
-
Lee Sang-Jun
(Pacific R&D center)
;
-
Park Soo-Yeon
(Research institute of Physical education, Kyung Hee University)
;
- Kim Hong-Yeoul (Institute of Oriental Medicine, Kyung Hee University) ;
-
Park Seong-Kyu
(Department of Prescriptionology, College of Oriental Medicine, Kyung Hee University)
- 이승희 (서울향료 연구소) ;
-
이상준
(태평양 기술연구원 의약건강연구소)
;
-
박수연
(경희대학교 체육과학연구소)
;
- 김홍렬 (경희대학교 한의학연구소) ;
-
박성규
(경희대학교 한의과대학 방제학교실)
- Published : 2002.06.20
Abstract
We have examined the purgative effect of three Jechun-jun formulas in sprague dawley(SD) rat. Three jechun-jun formulas were Jechun-jun(Sample I ) and augmented Jechun-jun(Sample II) and augmented Jechun-jun add rhubarb(sample III ). We examined the amount and the humidity of feces in rat. The experimental animals were devided into four groups. as control group and three Jechun-jun (sample I, II, III). We administerd the water extract of sample I, II, III to rat per oral for 8days long. After every 24hours measured the amount of wet feces from rats in metabolic cage. Humidity rate of feces from rat was at first measure wet feces for 24hours (W) and measure dried feces (W1) and then we consider W-W1 as humidity. High humidity rate means constipation changes into moistening stool. The amount of wet feces and humidity rate of feces in rats were increased in sample I, II, III. Sample I has highest humidity rate of feces. so showed strong moistening effect. Sample II has mild effect in treating constipation. sample III has most amount of wet feces. in conclusion Jechun-jun has an effect of moistening stool. and augmented Jechun-jun add rhubarb has strong purgative effect.
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