Journal of Periodontal and Implant Science
- Volume 30 Issue 1
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- Pages.51-65
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- 2000
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- 2093-2278(pISSN)
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- 2093-2286(eISSN)
Immunohistochemical Study of the Expression of Bone Morphogenetic Protein(BMP-7) Following Regenerative Periodontal Surgery
생쥐 치아의 초기발생과정에서 Osteopontin mRNA의 발현
- Han, Kyung-Yoon (Department of Periodontology, College of Dentistry, Chosun University) ;
- Cho, Se-Yeol (Department of Periodontology, College of Dentistry, Chosun University) ;
- Lim, ki-Jungl (Department of Periodontology, College of Dentistry, Chosun University) ;
- Kim, Heung-Jung (Department of Oral Anatomy, College of Dentistry, Chosun University) ;
- Park, Ju-Cheol (Department of Oral Histology, College of Dentistry, Chosun University) ;
- Kim, Byung-Ock (Department of Periodontology, College of Dentistry, Chosun University)
- 한경윤 (조선대학교 치과대학 치주과학교실) ;
- 조세열 (조선대학교 치과대학 치주과학교실) ;
- 임기정 (조선대학교 치과대학 치주과학교실) ;
- 김흥중 (조선대학교 치과대학 구강해부학교실) ;
- 박주철 (조선대학교 치과대학 구강조직학교실) ;
- 김병옥 (조선대학교 치과대학 치주과학교실)
- Published : 2000.03.30
Abstract
Extracellular matrix component is degraded by enzymes of thematrix metalloproteinases(MMPs). MMPs are produced by both hemopoietic and structural cells. Increased activity of MMP-3 in periodontium is strongly associated with inflammatory periodontal disease. The purpose of the present study was to estimate the effect of BMP-7 on regeneration of periodontium. The optical density was measured by microwell plate reader at 450 nm.The difference of the optical density and the relative activity ofMMP-3 according to the concentration were statistically analyzed by one way ANOVA. The results were as follows: 1. Tetracycline-HCl showed the tendency to inhibit the activity of MMP-3 at the concentration lower than
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