Isoflavonoids and Alkaloids from Spartidium saharae

  • Abdel-Halim, Osama B. (Dept. of Chemistry, South Dakota State Univ.) ;
  • Abdel-Fattah, Hosny A. (Dept. of Pharmacognosy, Faculty of Pharmacy, Mansoura University) ;
  • Halaweish, Fathi T. (Dept. of Pharmacognosy, Faculty of Pharmacy, Mansoura University) ;
  • Halim, Ahmed F. (Dept. of Pharmacognosy, Faculty of Pharmacy, Mansoura University)
  • Published : 2000.12.01

Abstract

A new isoflavone, $(+)-4'-O-methyl-8-C-{\beta}-D-glucopyranosylgenistein$, was isolated from the aerial parts of Spartidium saharae together with the known isoflavone, $(+)-8-C-{\beta}-D-glucopyranosylgenistein$ as well as dipiperidine alkaloids, (+)-ammodendrine and (+)-N-acetyl hystrine. Details of their structure elucidation are based on chemical and spectroscopic methods. N-formyl ammodendrine was detected by GC-MS. The potential chemotaxonomic value of the alkaloid content is explored. Cytotoxic activity has been determined for both alcoholic extract and isolated compounds.

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