Abstract
Background: In neonatal respiratory distress syndrome patients, various types of pulmonary air leak contributes to elevate morbity and mortality. Although early surgical interventions can provide better results in several cases, whole clinical outcomes are poor. This study was designed to investigate the clinical aspects of pulmonary air leak in the neonatal respiratory distress syndrome patients and major contributing factors to mortality. Material and Method : We retrospectively evaluated 48 cases of pulmonary air leak in the neonatal respiratory distress syndrome patients from September 1994 to May 1997. Result: There were 15 cases of primary and 33 cases of secondary pulmonary air leakages. The prominent manifestations were pure interstitial emphysema in 19 cases(39.9%) and combined pneumothorax in 19 cases(39.9%). In clinical aspects, normal birth weight was dominant(83.4%), the onset occurred within 24 hours was in 28 cases(58.8%). The pulmonary diseases were meconium aspiration syndrome(25.2%) and hyaline membrane disease(33.2%). The overall hospital mortality was 25.2%, and the majority were hyaline membrane diseases. Conclusion: Although the overral mortality rate of these diseases were high, more detailed studies about immediate treatement, perinatal prevention, intensive care to geriatric problems were needed individually to improve outcomes.
1994년 9월에서 1997년 5월까지 신생아 호흡곤란을 보였던 환아들중 폐외 공기 누출을 나타내었던 48례를 대상으로 그 임상 양상을 분석하였는데 일차성 15례, 이차성 33례를 보였고, 순수 폐간질 기종이 19례, 다른 병변과 동반된 기흉이 19례 있었다. 정상 체중아가 많고 24시간내 증상 발현의 경우가 많았다. 폐 질환으로는 유리질 막증, 태변 흡입 증후군, 폐렴 등이 있었다. 25.2%의 원내 사망율을 보였고 유리질막증 환자에서 많았다.