Acknowledgement
Supported by : 한양대학교
Korean Journal of Biological Psychiatry (생물정신의학)
- Volume 5 Issue 2
- /
- Pages.210-214
- /
- 1998
- /
- 1225-8709(pISSN)
- /
- 2005-7571(eISSN)
An Association Study of COMT Gene Polymorphism with Korean Schizophrenics
정신분열병과 Catechol-O-methyltransferase(COMT) 유전자 다형성의 연합
- Song, En-Sook (Department of Biochemistry and Molecular Biology, Hanyang University) ;
-
Yang, Byung-Hwan
(Department of Neuropsychiatry, College of Medicine and The Mental Health Research Institute, Hanyang University)
;
- Park, Kang-Kyu (Seoul National Mental Hospital) ;
- Lee, Yu-Sang (Yong-In Mental Hospital) ;
- An, Eun-Soog (Yong-In Mental Hospital) ;
- Oh, Dong-Yul (Seoul National Mental Hospital) ;
- Kim, Jong-Won (Department of Psychiatry, College of Medicine, Ehwa University) ;
-
Choi, Ihn-Geun
(Department of Neuropsychiatry, College of Medicine, Hallym University)
;
- Kim, Gil-Sook (Seoul National Mental Hospital) ;
-
Chai, Young-Gyu
(Department of Biochemistry and Molecular Biology, Hanyang University)
- 송은숙 (한양대학교 생화학 및 분자생물학과) ;
-
양병환
(한양대학교 정신건강연구소 및 의과대학 신경정신과학교실)
;
- 박강규 (국립서울정신병) ;
- 이유상 (용인정신병원) ;
- 안은숙 (용인정신병원) ;
- 오동열 (국립서울정신병) ;
- 김종원 (이화여자대학교 의과대학 정신과학교실) ;
-
최인근
(한림대학교 의과대학 신경정신과학교실)
;
- 김길숙 (국립서울정신병) ;
-
채영규
(한양대학교 생화학 및 분자생물학과)
- Published : 1998.12.25
Abstract
An association study with Korean schizophrenic patients(N=84) and normal controls(N=87) was performed to find the relationship between catechol-O-methyltransferase(COMT) gene polymorphism and schizophrenia using polymerase chain reaction-restriction fragment length polymorphism. When we compared the allele and genotype frequencies of Bgl I COMT gene polymorphism in schizophrenics and normal controls, there was no significant difference between two groups. Our results do not support an association between the Bgl I polymorphism of COMT gene and schizophrenia.