약학회지 (YAKHAK HOEJI)
- 제42권6호
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- Pages.572-575
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- 1998
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
키토산 유도체의 담즙산 흡착 활성
The Bile Acid Absorption Activity of Chitosan Derivatives
- Lee, Ai-Leen (College of Pharmacy, Ewha Womans University) ;
- Lee, Kang-Man (College of Pharmacy, Ewha Womans University)
- 발행 : 1998.12.01
초록
Chitosan has been known to have hypocholesterolemic and hypolipidemic effects in animal studies. Chitosan also absorbs bile acids in vitro and in vivo, which might result in the hypocholesterolemic action. Trialkyl chitosan derivatives were prepared and tested for bile acid absorption activity in vitro. The derivatives showed enhanced absorption capacities which were comparable to cholestyramine.