Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Isolation and Quantitative Determination of Patchouli alcohol from Pogostemon cablin Benth.

광곽향(Pogostemon cablin Benth.)으로부터 Patchouli alchol의 분리 및 함량분석

  • Kim, Ju-Sun (Natural Products Research Institute, Seoul National University) ;
  • Chi, Hyung-Joon (Natural Products Research Institute, Seoul National University) ;
  • Won, Do-Hee (Korea Food and Drug Administration) ;
  • Kang, Sam-Sik (Natural Products Research Institute, Seoul National University)
  • 김주선 (서울대학교 천연물과학연구소) ;
  • 지형준 (서울대학교 천연물과학연구소) ;
  • 원도희 (식품의약품안전본부) ;
  • 강삼식 (서울대학교 천연물과학연구소)
  • Published : 1998.03.30
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Abstract

A method for isolation and quantitative determination of patchouli alcohol from Pogostemonis Herba (Pogostemon cablin) has been developed. Isolation of patchouli alcohol was achieved by column chromatography employing the normal-phase gradient separation system n-hexane-ether on silica gel column. The GC method for quantitative determination of patchouli alcohol provided a method for standardization of the raw drug. It suggested that the average content of patchouli alcohol in Pogostemonis Herba is about 0.26%.

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