생약학회지 (Korean Journal of Pharmacognosy)
- 제27권3호
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- Pages.196-206
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- 1996
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
한약수치에 관한 연구(제5보) - 수치에 의한 감초의 성분변화 및 생리활성 -
Studies on the Processing of Crude Drugs (V) - On the Constituents and Biological Activities of Glycyrrhizae Raidx by Processing -
- Hong, Nam-Doo (Natural Products Research Institute of Bangchon, Hankooksinyak Co. Ltd) ;
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Kim, Nam-Jae
(East-West Medical Research Institute, Kyung-Hee University)
- 발행 : 1996.09.30
초록
In order to characterize the chemical change, of the constituents and pharmacological transformation of Glycyrrhizae Radix(GR) which may occur during its processing, processed GR has been investigated in comparison with unprocessed GR. It was found that glycyrrhizin(GL) and other several constituents contained in GR were remarkably changed by processing, and the decrease of contents of GL was identified by making use of thin layer chromatography-chromatoscanner. And also, it was found that glycyrrhetic acid (GA) was identified from processed GR. We recognized that commonly processed GR showed less hemolytic effect than unprocessed GR and processed GR at
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