생약학회지 (Korean Journal of Pharmacognosy)

  • 제26권4호
  • /
  • Pages.368-376
  • /
  • 1995
  • /
  • 0253-3073(pISSN)
  • /
  • 2288-9299(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

왕대잎(Phyllostachys bambusoides S. et Z.)의 지질과산화억제활성

Antilipoperoxidatant Effects of Leaves of Phyllostachys bambusoides S. et Z.

  • 김남재 (경희대학교 동서의학연구소) ;
  • 이석주 (경희대학교 약학대학) ;
  • 권창호 (경희대학교 약학대학) ;
  • 홍남두 (경희대학교 동서의학연구소)
  • Kim, Nam-Jae (East-West Medical Research Institute, Kyung-Hee University) ;
  • Lee, Suk-Joo (College of Pharmacy, Kyung-Hee University) ;
  • Kwon, Chang-Ho (College of Pharmacy, Kyung-Hee University) ;
  • Hong, Nam-Doo (East-West Medical Research Institute, Kyung-Hee University)
  • 발행 : 1995.12.30
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초록

The leaf of Phyllostachys bambusoides S. et Z. (Gramineae) has been used in traditional herbal medicine as a antipyretics, antitussives and antidiuretcs, etc, in Korea, China and Japan. In order to investigate the effects on antilipoperoxidation and liver protective effect, the leaf of Phyllostachys bambusoides S. et Z. was extracted by water and then fractionated with butanol. The water extract and BuOH soluble fraction strongly exhibited antilipoperoxidatant effect in rat liver homogenate intoxicated with $CCl_4$. The BuOH fraction significantly suppressed the increases of s-GOT, s-GPT and s-LDH activities in injuried rats induced by $CCl_4$. And the BuOH fraction inhibited significantly the decrease of the body weight and showed the antilipoperoxidatant effect in liver and kidney in $CCl_4$ intoxicated rats.

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