Microbiology and Biotechnology Letters (한국미생물·생명공학회지)

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Correlation between Anticomplementary and Antitumor Activity of the Crude Polysaccaride from Ganoderma Iucidum IY009

Ganoderma lucidum IY 009조다당 분획들의 항암활성과 항보체활성간의 상호관계

  • Lee, Kweon-Haeng (Department of Food Engineering, College of Engineering, Yonsei university) ;
  • Lee, June-Woo (Biotechnology Lab., Central Institute of Research, Il Yang Pharmaceutical Co. Ltd.) ;
  • Han, Man-Deuk (Biotechnology Lab., Central Institute of Research, Il Yang Pharmaceutical Co. Ltd.) ;
  • Jeong, Hoon (Biotechnology Lab., Central Institute of Research, Il Yang Pharmaceutical Co. Ltd.) ;
  • Kim, Young-Il (Biotechnology Lab., Central Institute of Research, Il Yang Pharmaceutical Co. Ltd.) ;
  • Oh, Doo-Whan (Department of Food Engineering, College of Engineering, Yonsei university)
  • 이권행 (연세대학교 식품공학과) ;
  • 이준우 (일양약품(주) 중앙연구소 생물공학연구실) ;
  • 한만덕 (일양약품(주) 중앙연구소 생물공학연구실) ;
  • 정훈 (일양약품(주) 중앙연구소 생물공학연구실) ;
  • 김영일 (일양약품(주) 중앙연구소 생물공학연구실) ;
  • 오두환 (연세대학교 식품공학과)
  • Published : 1994.02.01
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Abstract

Antitumor polysaccharides were known to activate complement system and to increase specific serum proteins in mouse, and researcher reported that antitumor activity of polyasccharides might be correlated with their biological properties such as activation of complement system and increase of specific protein $L_{A}$, $L_{B}$ and $L_{C}$ within the mouse serum. In case of several Ganoderma lucidum, there was no correlation between their antitumor activities and their bioloical properties, but the antitumor activities against sarcoma 180 of the alkali extracted crude polysaccharide fractions of the Ganoderma lucidum IY 009. AS, T, AI and M were correlated with their bioloical properties such as anticomplementary activity and intensity of mouse serum protein $L_{A}$, $L_{B}$ and $L_{C}$.

Keywords

References

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