• Title/Summary/Keyword: mouse serum protein L , Ls and Lc

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Correlation between Anticomplementary and Antitumor Activity of the Crude Polysaccaride from Ganoderma Iucidum IY009 (Ganoderma lucidum IY 009조다당 분획들의 항암활성과 항보체활성간의 상호관계)

  • Lee, Kweon-Haeng;Lee, June-Woo;Han, Man-Deuk;Jeong, Hoon;Kim, Young-Il;Oh, Doo-Whan
    • Microbiology and Biotechnology Letters
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    • v.22 no.1
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    • pp.45-51
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    • 1994
  • Antitumor polysaccharides were known to activate complement system and to increase specific serum proteins in mouse, and researcher reported that antitumor activity of polyasccharides might be correlated with their biological properties such as activation of complement system and increase of specific protein $L_{A}$, $L_{B}$ and $L_{C}$ within the mouse serum. In case of several Ganoderma lucidum, there was no correlation between their antitumor activities and their bioloical properties, but the antitumor activities against sarcoma 180 of the alkali extracted crude polysaccharide fractions of the Ganoderma lucidum IY 009. AS, T, AI and M were correlated with their bioloical properties such as anticomplementary activity and intensity of mouse serum protein $L_{A}$, $L_{B}$ and $L_{C}$.

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