생약학회지 (Korean Journal of Pharmacognosy)

  • 제23권2호
  • /
  • Pages.73-76
  • /
  • 1992
  • /
  • 0253-3073(pISSN)
  • /
  • 2288-9299(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

고들빼기의 고콜레스테롤혈증 개선효과

Further Study on the Anti-hypercholesterolemic Effect of Ixeris sonchifolia

  • 양한석 (부산대학교 약학과) ;
  • 최재수 (부산수산대학교 식품영양학과) ;
  • 이지현 (부산수산대학교 식품영양학과)
  • Young, Han-Suk (College of Pharmacy, Pusan National University) ;
  • Choi, Jae-Sue (Dept. of Nutrition and Food Science, National Fisheries University of Pusan) ;
  • Lee, Ji-Hyon (Dept. of Nutrition and Food Science, National Fisheries University of Pusan)
  • 발행 : 1992.06.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Effect of various fractions prepared from the methanol extract of Ixeris sonchifolia and flavonoids isolated from the extract on hypercholesterolemic mice were examined. When various fractions $(CHCl_3,\;Interphase,\;EtOAc,\;n-BuOH\;and\;H_2O)$were administered to mice, the Interphase material produced a significant activity. Total cholesterol level in the Interphase material-treated group given doses of 25 and 50mg was decreased significantly by as much as 16% and 30%, respectively. Among the isolated flavonoids, cynaroside caused a significant hypocholesterolemic activity.

키워드