Studies on the Efficacy of Combined Preparation of Crude Drug (XXV) -Effects of Soeuminsowhapwon on Anticonvulsion, Analgesic, Antipyretic, Sedative, Isolated Ileum, Blood Vessels and Blood Pressure-

생약(生藥) 복합제제(複合製劑)의 약효(藥效) 연구(硏究)(제25보)(第25報) -소음인소합원(小陰人蘇合元)이 항경련(抗痙攣), 진통(鎭痛), 해열(解熱), 진정(鎭靜), 적출장관(摘出腸管), 혈관(血管) 및 혈압(血壓)에 미치는 영향(影響)-

In order to investigate experimentally the clinical effects of Soeuminsohapwon that was prescribed to cure cerebral hemorrhage, palpitation etc, the author tested various activities of extract from the Soeuminsohapwhangwon by the method prescribed in the experimental part. The results of the studies were summarized as follows: Suppressive action was not shown on the convulsion induced by strychnine, but significant effect was noted on the convulsion induced by picrotoxin and caffeine. In acetic acid method, analgesic effect was noted. A prolongation of anesthetic time by pentobarbital sodium and antipyretic effect was observed. Relaxing action was noted on the ileum of mice, also same effect was recognized on contraction of the ileum due to acetylcholine, barium chloride and histamine. The expansion of blood vessels by relaxation of smooth muscle and hypotensive action were noted. According to the above results, effects based on oriental medical references were approximate to the actual experimental results.