Studies on the Development of Antibiotics in Korea(I) -The Distribution of Antibiotic-producing Streptomyces in the Western Area of Korea(I)-

항생물질(抗生物質)의 개발(開發)을 위한 국내자원(國內資源) 조사(調査) 연구(硏究)(I) -한국(韓國) 서해안(西海岸) 지방(地方)의 토양중(土壤中) 항균성(抗菌性) 방선균(放線菌)의 분포(分布)-

The antibiotic-producing Streptomyces strains were isolated from the soils of various localities in Yeang-Kwang and tested for the activity against some of gram positive and negative microorganisms, especially against Pseudomonas aeruginosa. The results are summarized as follows. 1. A total of 1464 Streptomyces strains were isolated from 336 soil samples. Of all the strains tested, 636 strains of the isolates showed antibiotic activity against either gram positive or negative test organisms. And 408 of the 636 strains were strongly active against one or all of those test­organisms. 2. Ninety-three of Streptomyces strains among the active isolates showed the antibiotic activity against Pseudomonas aeruginosa, and 24 of 93 strains showed the strong antibiotic activity against all of the test organisms i.e. Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Salmonella typhi and Shigella jlexneri. 3. Antibiotic-producing Streptomyces strains active against Pseudomonas aeruginosa were isolated from the soil samples taken from vegetable field, paddy field, sandy ground and roadway, but not isolated from the soil taken from dwelling area, grass field and piers.