Apnea of Somatic Cell Cloned Piglets with Congestion is Caused by Cardiopulmonary

  • Lee, So-Young (Major of Dairy Science, Division of Applied Life Science) ;
  • Park, Mi-Ryeung (Major of Dairy Science, Division of Applied Life Scienc) ;
  • Cho, Seong-Keun (Major of Dairy Science, Division of Applied Life Scienc) ;
  • Park, Yun-Jung (Major of Dairy Science, Division of Applied Life Scienc) ;
  • Kwon, Deug-Nam (Major of Dairy Science, Division of Applied Life Scienc) ;
  • Lee, Eun-Kyeong (Major of Dairy Science, Division of Applied Life Scienc) ;
  • Son, Woo-Jin (College of Veterinary Medicine, Gyeongsang National University) ;
  • Kim, Jin-Hoi (Major of Dairy Science, Division of Applied Life Science)
  • Published : 2004.06.01

Abstract

In this study, we generated 40 somatic cell cloned (scNT) piglets. Of these, three displayed congestion in both liver and lung, and died within the first week of life. Two-dimensional gel electrophoresis experiments revealed changes in the responses of several detoxification-related proteins to stress and inflammation. As a result, congestive livers and lungs displayed extensive hepatopneumonic apoptosis.(omitted)

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