Effect of Acanthopanax koreanum on D-galactosamine and lipopolysaccharide-induced fulminant hepatitis

  • Park, Eun-Jeon (Department of Pharmacy, Wonkwang University) ;
  • Nan, Ji-Xing (College of Pharmacy, Chungnam National University) ;
  • Zhao, Yu-Zhe (Anticancer Research Laboratory, Korea Research Institute of Bioscience and Biotechnolog) ;
  • Lee, Sung-Hee (Anticancer Research Laboratory, Korea Research Institute of Bioscience and Biotechnolog) ;
  • Kim, Young-Ho (Anticancer Research Laboratory, Korea Research Institute of Bioscience and Biotechnolog) ;
  • Nam, Jeong-Bum (Anticancer Research Laboratory, Korea Research Institute of Bioscience and Biotechnolog) ;
  • Lee, Jung-Joon (Anticancer Research Laboratory, Korea Research Institute of Bioscience and Biotechnolog) ;
  • Sohn, Dong-Hwan (Anticancer Research Laboratory, Korea Research Institute of Bioscience and Biotechnology)
  • Published : 2003.04.01

Abstract

The roots and rhizome of Acanthopanax koreanum are used as folk medicine to ameliorate hepatitis in Korea. The ability of A. koreanum to protect mice from fulminant hepatitis induced in mice by D-galactosamine and lipopolysaccharide was evaluated. Preparations of A. koreanum used were an ethanol extract, and the ethanol-soluble and ethanol-insoluble components of the water extract. (omitted)

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