Swelling and Drug Release Behavior of Tablets Coated with Aqueous Hydroxypropyl Methylcellulose Phthalate (HPMCP) Nanoparticles

  • Published : 2003.04.01

Abstract

Organic solvent-based enteric coating technology using hydroxypropyl methylcellulose phthalate (HPMCP) has been developed for many years due to low water solubility of HPMCP. In this work, aqueous HPMCP nanoparticles (HPMCP-NPs) were prepared by neutralization emulsification method using HPMCP powder and ammonium hydroxide (NH40H) in the absence of any organic solvent and emulsifier. (omitted)

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