13 Weeks Repeated-Dose Toxicity Studies of the Siho(Bupleuri Radix) in Rats

  • Myung Sil Hwang (Department of General Toxicology, National Institute of Toxicological Research) ;
  • Dong Han Shin (Department of General Toxicology, National Institute of Toxicological Researc) ;
  • Young Na Yum (Department of General Toxicology, National Institute of Toxicological Researc) ;
  • Jin Hong Ahn (Department of General Toxicology, National Institute of Toxicological Researc) ;
  • Jun Chul Park (Department of General Toxicology, National Institute of Toxicological Researc) ;
  • Ji Sun Lee (Department of General Toxicology, National Institute of Toxicological Researc) ;
  • Yun Jin Park (Department of General Toxicology, National Institute of Toxicological Researc) ;
  • Ji On Kim (Department of General Toxicology, National Institute of Toxicological Researc) ;
  • Shin Hee Kim (Department of General Toxicology, National Institute of Toxicological Research)
  • Published : 2003.05.01

Abstract

The Bupleuri Radix, called as "Siho" in Korea has been widely used in Korea, China, and Japan as Traditional Herbal Medicine since ancient times and currently. Although saikosaponins isolated from the Bupleuri Radix had metabolic and anti-inflammatory action, it's toxicity was not screened completely. Recently, many herbal medicines are imported from China but safety of these was not evaluated. (omitted) (omitted)

Keywords