Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.05a
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- Pages.56-56
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- 2003
Arsenite-induced Hepatotoxicity in Chang Liver and Clone 9 Cells
- Yum, Young-Na (Department of General Toxicology, National Institute of Toxicological Research) ;
- Ahn, Jin-Hong (Department of General Toxicology, National Institute of Toxicological Researc) ;
- Kim, Gi-Dae (Department of General Toxicology, National Institute of Toxicological Researc) ;
- Hwang, Myung-Sil (Department of General Toxicology, National Institute of Toxicological Researc) ;
- Kim, Sheen-Hee (Department of General Toxicology, National Institute of Toxicological Researc) ;
- Lim, Chul-Joo (Department of General Toxicology, National Institute of Toxicological Researc) ;
- Yang, Ki-Hwa (Department of General Toxicology, National Institute of Toxicological Researc) ;
- Kim, Dae-Kyung (College of Pharmacy, Chungang University) ;
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Cho, Dae-Hyun
(Department of General Toxicology, National Institute of Toxicological Research)
- Published : 2003.05.01
Abstract
The reactivity and toxicity of arsenic compounds depend on the their oxidative states. Exposure to arsenic causes many human health effects, including cardiovascular, hepatic and renal disease, in addition to cancer in kidney, liver, lung, urinary bladder and skin. The cytotoxic effects of arsenite on normal hepatocyte, which most of its biotranfomation takes place. (omitted)
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