Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.290.2-290.2
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- 2002
Hepatoprotective effects of Platycodi Radix on carbon tetrachloride-induced liver damage in mice
- Lee, Kyung-Jin (Dept. of Pharmacy and Research Center for Proteineous Materials, Chosun Univ.) ;
- Park, Sung-Jun (Korea Research Institute of Chemical Technolog) ;
- Choi, Chul-Yung (Dept of Food Nutrition, College of Chinju) ;
- Kim, Young-Sup (Dept of Food Nutrition, College of Chinju) ;
- Chung, Young-Chul (Dept of Food Nutrition, College of Chinju) ;
- Jeong, Hye-Gwang (Dept of Food Nutrition, College of Chinju)
- Published : 2002.10.01
Abstract
The protective effects of a Platycodi Radix (Changkil: CK), the root of Platycodon grandiflorum A. DC (Campanulaceae). on carbon tetrachloride-induced hepatotoxicity and the possible mechanisms involved in this protection were investigated in mice. Pretreatment with CK prior to the administration of carbon tetrachloride significantly prevented the increased serum enzymatic activities of alanine and aspartate aminotransferase in a dose-dependent manner. (omitted)
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