Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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The Effect of Chondroitin Sulfate against Oxidative Stress and Atherosclerosis In Ovariectomized Rat

  • Ha, Bae-Jin (Major in Bioscience and Biotechnology, Division of New Materials and Biotechnology, Silla University) ;
  • Lee, Jin-Young (Department of Biochemistry, College of Medicine, Inje University)
  • Published : 2002.10.01
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Abstract

The surgically ovariectomized rat induces aging by reactive oxyyen species(ROS) generation. Free oxygen radicals have been proposed as important causative agents of aging. The purpose of this study was to investigate the effect of Chondroitin Sulfate(CS) to prevent ovariectomy(OVX) induced oxidative stress and atherosclerosis. The OVX rats were given intraperitoneally CS at dose of 100mg/kg and 200mg/kg daily for fifteen weeks. (omitted)

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