Analysis of vasopressin-induced Ca2+ influx in rat hepatocytes

  • Kim, Hyun-Sook (Laboratory of Pharmacology, College of Pharmacy, Pusan National University) ;
  • Im, Dong-Soon (Laboratory of Pharmacology, College of Pharmacy, Pusan National University)
  • Published : 2002.10.01

Abstract

To analyze vasopressin-induced Ca$\sub$2+/ influx in liver cells, rat hepatocytes were isolated and attached to collagen-coated cover slips. Using fura-2, a Ca$\sub$2+/-sensing dye, changes in intracellular Ca$\sub$2+/ concentration by vasopressin were monitored. Results in this communication suggested that vasopressin-induced Ca$\sub$2+/ influx consists of two distinguishable components. One was present for a short time and the other was for a long time until it happened. (omitted)

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