Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

PLATYCODIN D, NOT D3, CAUSES VASODILATATION IN THE RAT

  • Lim, Dong-Yoon (Department of Pharmacology, College of Medicine, Chosun University) ;
  • Kee, Yeong-Woo (Natural Products Research Institute, Seoul National University) ;
  • Lee, Eun-Bang (Natural Products Research Institute, Seoul National University)
  • Published : 2002.10.01
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Abstract

The purpose of the present study was to determine the effects of platycodin D and D3 on the contractile force of the isolated rat aorta and blood pressure of the anesthetized rat. and also to establish the mechanism of action. The phenylephrine (10 $\mu$M)-induced contractile responses were greatly inhibited in the presence of platycodin D (4 ∼ 24 $\mu$g/$m\ell$) in a dose-dependent fashion. (omitted)

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