대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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- Pages.260.1-260.1
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- 2002
Epigallocatechin Gallate inhibits Prostagladins Generation by Suppression of cPLA2 Activity on Arachidonic Acid Metabolism in LPS-Stimulated RAW264.7 Cells
- Son, Dong-Ju (College of Natural Sciences, Soonchunhyang University) ;
- Akiba, Satoshi (Department of Pathological Biochemistry, Kyoto Pharmaceutical University) ;
- Sato, Takashi (Department of Pathological Biochemistry, Kyoto Pharmaceutical University) ;
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Park, Young-Hyun
(College of Natural Sciences, Soonchunhyang University)
;
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Yun, Yeo-Pyo
(College of Pharmacy, Chungbuk National University)
- 발행 : 2002.10.01
초록
Green tea contains several antioxidants including polyphenols of the catechin. which have been shown to act in vitro and in vivo as anti-inflammatory. anti-viral and anti-tumor drugs. Prostaglandins (PGs) are a family of intercellular and intracellular messengers derived from arachidonic acid(AA) by phospholipase(PL) and cyclooxygenase(COX). These mediators exert a wide range of effects on processes such as smooth muscle tone. vascular permeability, cellular proliferation. and inflammatory/immune function. (omitted)
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