Effects of Benomyl and Lindane during late pregnancy in the rat

  • Moon, Hyun-Ju (Endocrine Toxicology Division, National Institute of Toxicological Research, KFDA) ;
  • Shin, Jae-Ho (Endocrine Toxicology Division, National Institute of Toxicological Research, KFDA) ;
  • Lee, Sujung (Endocrine Toxicology Division, National Institute of Toxicological Research, KFDA) ;
  • Kang, Il-Hyun (Endocrine Toxicology Division, National Institute of Toxicological Research, KFDA) ;
  • Kim, Tae-Sung (Endocrine Toxicology Division, National Institute of Toxicological Research, KFDA) ;
  • Hoon Bae (Endocrine Toxicology Division, National Institute of Toxicological Research, KFDA) ;
  • Ryu, Seung-Yeoul (Endocrine Toxicology Division, National Institute of Toxicological Research, KFDA) ;
  • Seok, Ji-Hyun (Endocrine Toxicology Division, National Institute of Toxicological Research, KFDA) ;
  • Ahn, Ji-Yeon (Endocrine Toxicology Division, National Institute of Toxicological Research, KFDA)
  • Published : 2002.11.01

Abstract

These experiments tested whether exposure to benomyl (BN) or lindane (LD) during late pregnancy affect the development of reproductive tract in adult offspring. Timed pregnant Sprague Dawley rats (N=7∼8/treatment) were gavaged with LD (1, 5, or 10 mg/kg), BN (50, 250, or 500 mg/kg), or com oil on gestation days 15∼19.(omitted)

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