INVESTIGATION OF IN VITRO AND IN VIVO ESTROGENIC OR ANTIESTROGENIC ACTIVITY OF CYPERMETHRIN

  • Kim, Soon-Sun (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Rhee, Gyu-Seek (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Kwack, Seung-Jun (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Sohn, Kyung-Hee (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Kim, So-Hee (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Lee, Rhee-Da (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • An, Sang-Mi (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Ki-Eun. Jeong (College of Pharmacy, Ewha Womans University) ;
  • Sheen, Yhun-Yhong (College of Pharmacy, Ewha Womans University)
  • Published : 2002.11.01

Abstract

In the present study, estrogenic or antiestrogenic activity of cypermethrin, a pyrethroid insecticide was investigated. We used immature rat uterotrophic assay, estrogen-responsive calbindin-D9k (CaBP-9k) gene expression assay and luciferase reporter gene assay for measure of estrogenic potential of cypermethrin.(omitted)

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