CHRONIC TOXICITY OF MICROCYSTIN-LR IN MICE

  • Kim, Yeo-Jung (College of veterinary medicine, Chonbuk national university) ;
  • Lim, Chae-Woong (College of veterinary medicine, Chonbuk national university) ;
  • Rim, Byung-Moo (College of veterinary medicine, Chonbuk national university)
  • Published : 2002.11.01

Abstract

This study is to characterize the microscopical and ultrastructural changes in chronic exposure of Microcystin-LR (MCLR), a cyclic heptapeptide hepatotoxin, comparing to those in acute lethal toxicity. Female ICR mice were injected intraperitoneally with 10, 20, 30,$\mu\textrm{g}$/kg of MCLR every 3 day for 27 days.(omitted)

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