Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.10a
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- Pages.190-190
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- 2001
COMPARATIVE GENOMIC HYBRIDIZATION STUDIES ON CHOLANGIOCARCINOMA IN KOREA
- Lee, Chul-Hoon (Department of Medical Genetics) ;
- Park, Bu-Young (Department of Molecular Biology and Pharmacology, C＆C Research Laboratorie) ;
- Kim, Min--Kyoung (Department of Medical Genetic) ;
- Jee- Hong Kyhm (Department of Medical Genetic) ;
- Park, Ho-Soon (Department of Internal, College of Medicine, Hanyang University) ;
- Cho, Youl-Hee (Department of Medical Genetics)
- Published : 2001.10.01
Abstract
The elucidation of the genetic changes of cholangiocarcinoma is very important for understanding the molecular mechanism of carcinogenesis and progression of cholangiocarcinoma. In order to identify the gains or losses of the copy number of DNA sequence in cholangiocarcinoma, we used comparative genomic hybridization to study 33 cases of cholangiocarcinoma. The whole DNAs from each tumor tissue were labeled with different fluorochromes and then simultaneously hybridized to normal metaphase spread chromosomes.(omitted)
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