Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.10a
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- Pages.131-131
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- 2001
SUPPRESSIVE EFFECTS PF XAMTJPRRJOZOL ON INDUCIBLE CYCLOOXYGENASE (COX-2) AND NITRIC OXIDE SYNTHASE (iNOS) ACTIVITY IN MOUSE MACROPHAGE CELLS
- Huh, Sun-Kyung (College of Pharmacy, Ewha Womans University) ;
- Park, Hyen-Joo (College of Pharmacy, Ewha Womans University) ;
- Kim, Sun-Sook (College of Pharmacy, Ewha Womans University) ;
- Oh, O-Jin (College of Pharmacy, Ewha Womans University) ;
- Min, Hye-Young (College of Pharmacy, Ewha Womans University) ;
- Park, Kwang-Kyun (College of Pharmacy, Ewha Womans University) ;
- Chung, Won-Yoon (College of Pharmacy, Ewha Womans University) ;
- Hwang, Jae-Kwan (Bioproducts Research Center, Yonsei University) ;
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Lee, Sang-Kook
(College of Pharmacy, Ewha Womans University)
- Published : 2001.10.01
Abstract
Prostaglandins and nitric oxide produced by inducible cyclooygenase (COX-2) and nitric oxide synthase (iNOS), respectively, have been implicated as important mediators in the process of inflammation and carcinogenesis. On this line, the potential COX-2 or iNOS inhibitors have been considered as anti-inflammatory and cancer chemopreventive agents.(omitted)
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