Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.10a
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- Pages.132-132
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- 2001
EFFECT OF CAPSAICIN ON LPS-INDUCED PROSTAGLANDIN E2 PRODUCTION BY MURINE PERITONEAL MACROPHAGES
- Kim, Chu-Sook (Dept. of Food Sci. and Nutr.,) ;
- Kim, Byung-Sam (Dept. of Biol. Sci) ;
- Han, In-Seob (Dept. of Biol. Sci) ;
- Chei, Suck-Young (Dept. of Food Sci. and Nutr.) ;
- Kwon, Byung-Se (Immunomodulation Research Center, University of Ulsa) ;
- Rina Yu (Dept. of Food Sci. and Nutr.,)
- Published : 2001.10.01
Abstract
Proinflamamtory mediators such as prostaglandins (PGs), cyclooxygenase-2 (COX-2), and inducible nitric oxide synthase (iNOS) are known to be key mediators in pathogenesis of inflammatory diseases. Capsaicin, the major ingredient of hot pepper, is considered to elicit anti-inflammatory property. In this study, the effect of capsaicin on the prostaglandin E
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