Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.05a
- /
- Pages.131-131
- /
- 2001
PHARMACOLOGICAL EFFECTS OF NOVEL QUINOLINEDIONE COMPOUNDS ON INHIBITION OF DRUG-INDUCED RELAXATION OF RAT AORTA AND THEIR PUTATIVE ACTION MECHANISM
- Lee, Jung-Ah (College of Pharmacy, Ewha Womans University) ;
- Ryu, Chung-Kyu (College of Pharmacy, Ewha Womans University) ;
-
Chung, Jin-Ho
(College of Pharmacy, Seoul National University)
;
- Kim, Hwa-Jung (College of Pharmacy, Ewha Womans University)
- Published : 2001.05.01
Abstract
Two 6-(fluorinated-phenylamino)-5, 8-quinolinedione derivatives, OQ21 and OQ1, were newly synthesized as potent inhibitors of endothelial-dependent vasorelaxation. The purpose of the present study was to investigate the effect of OQ21 and OQ1 on different types of vasorelaxation and to pursue their action mechanisms. (omitted)
Keywords