• The Journal of Korean Medicine
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• v.29 no.2
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• pp.60-70
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• 2008

Objectives: The aim of the present investigation was to determine whether the finger photoplethysmography (PPG) of the young will become analogous to those of the old when the PPG harmonic components in the young decrease. Methods: The PPG was measured in 46 old men (21 males and 25 females) over the age of 60 years and 10 young men (5 males and 5 females). We acquired the representative pulse waveform of old men by averaging the PPG waveforms measured in the old men. after the PPG harmonic components in the young men were diminished with notch filtering, we compared the representative pulse waveform of old men and those of the young men. Results: The PPG waveform of the young males became analogous to the representative pulse waveform of the old as the PPG harmonic components in the young were diminished with notch filtering. Especially after the second harmonic component in the young was diminished with notch filtering, increase of the Pearson's correlation coefficient was prominent. On the other hand, the Pearson's correlation coefficient between the PPG waveforms of the young females and that of the old deceased after the second harmonic component diminished in the young. Conclusions: Decrease of the second harmonic component may be a precondition of typical age-related change of the pulse waveform in the healthy male.

• Journal of Yeungnam Medical Science
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• v.8 no.1
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• pp.191-197
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• 1991

Meconium peritonitis is an aseptic peritonitis caused by spill of meconium in the abdominal cavity through one or several intestinal perforations which have taken place during intrauterine life or early neonatal life. We experienced three cases of meconium peritonitis with ileal perforation in two cases 1 day-old male neonate and 2 day-old male neonate, respectively, which had the chief complaint of vomiting and abdominal distension, Literatures are reviewed, briefly.

• Advances in pediatric surgery
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• v.1 no.1
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• pp.85-94
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• 1995

Precocious puberty is difficult to define because of the marked variation in the age at which puberty begins normally, onset of puberty before 8 years of age in girls and 9 years in boys may be considered precocious. The etiology of precocious puberty in boys is usually idiopathic, but can result from adrenal and testicular tumors. The hepatoblastoma that produces hCG is a very rare functioning tumor known to cause precocious puberty in boys. Recently, author experienced one case of virilizing adrenal cortical adenoma in 22 month-old boy, one case of adrenal cortical carcinoma in 28 month-old boy, and one case of virilizing hCG-producing hepatoblastoma in 7 year-old boy and reviewed literatures.

• Proceedings of the Korean Society of Toxicology Conference
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• 2002.05a
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• pp.112-112
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• 2002

The age- and gender-related differences in acute toxicity and opening of blood-brain barrier induced by an organophosphate soman were investigated in rats. To assess acute toxicity, young (7 weeks old) and old (12 weeks old) male and female rats were subcutaneously administered with various dose levels of soman.(omitted)

• The Journal of Korean Obstetrics and Gynecology
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• v.32 no.1
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• pp.1-14
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• 2019

Objectives: This study was designed to investigate the effect of Bombycis corpus on reproductive dysfunction caused by aging. Methods: The experimental group was divided into three groups: a control group consisting of 8-week-old male ICR mice without any treatment, An aging-elicited group (AE group) consisting of 50-week-old ICR male mice without any treatment, and a Bombycis corpus treatment group (BC group) consisting of 50-week-old ICR male mice with treatment Bombycis corpus extract (0.78 g/kg/day) for 6 months. After 6 months, histochemistry and immunohistochemistry of the testis were performed to investigate the effects of Bombycis corpus on the reproductive dysfunction caused by aging. Results: In the first step, Bombycis corpus increased spermatogenesis and distribution of sertoli cells in the seminiferous tubule, increased BrdU positive reaction in the spermatogonium at the basal part of the seminiferous tubule, and decreased the apoptosis of Sertoli cells in the seminiferous tubule. In addition, Bombycis corpus increased AR positive in Sertoli cells and $17{\beta}-HSD$ positive in leydig cells. Finally, Bombycis corpus decreased 8-OHdG positivite reaction in the spermatids of the seminiferous lumen, caspase-3 positivity in leydig cells, and HDAC1 positivite reaction in sertoli cells. Conclusions: These results suggest that Bombycis corpus increases spermatogenesis, decreases apoptosis of leydig cells and Sertoli cells, increases the production and action of testosterone in the testis, and inhibits DNA damages and DNA transcripts decrease in the testis, Thereby improving reproductive dysfunction caused by aging.

• The Korean Journal of Food And Nutrition
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• v.9 no.1
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• pp.1-11
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• 1996

Male rats of 2 months-old(young), 6 months-old(adult) and 30 months-old(old)were fed 8 or 16 weeks to investigate the e(feats of dietary fat level on the lipid metabolism in the different stages of aging. The response of 30 month old rats to dietary fat level differed from either 2 or 6-months old rats. In 30-months old rats, dietary fat level had a little effect on weight gains, lipid content of serum as compared with other two age groups. Young rats showed higher body weight gain, F.S.R, and PER compared with aged rat. The younger and the more high fat fed the rats were, the more body weight gains, FER and PER showed. Weight of liver and kidney was increased in aged rats but ratio per unit weight of liver and kidney was not affected by age. Serum lipid content was higher in aged rat compared with the young and liver lipid content was higher in high fat diet fed rats. But TG of liver and serum was not changed with aging process. Intake, excretion and absorption of lipid was not changed by age of animals. but absorption was decreased as experimental period was increased.

• Journal of Digestive Cancer Research
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• v.10 no.1
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• pp.46-48
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• 2022

• Korean Journal of Health Education and Promotion
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• v.25 no.4
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• pp.29-42
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• 2008

Objective: To find the related factors and the symptoms of menopause in male workers. Method: This Study is targeted on 369 people(40's; 219, 50's; 150) who are married and being 40 years old or more with working for over ten year. Results: First, the symptom of menopause in proportion to age is, 40's appeared in order of 'Decrease in ability to play sport', and 50's appeared in order of 'Less strong erection'. Second, the symptom of menopause was higher from the difference between general characteristic and work characteristic when people have old age. Third, the symptom of menopause was lower from difference among life habits when people do some exercises regularly, and no overeating. Fourth, the symptom of menopause was much lower from the difference of subjective health state when people feel comfort without any disturbance to their daily life, as they feel much younger than their ages, and feel healthy. Fifth, the variables affected to the symptom of menopause were age, do exercise whether or not, subjective health state when people feel much younger than their ages, and feel healthy. Conclusion: the symptom of menopause is not only for women but also for men. And it is not only for people who are old but we could find some abilities from young ages, too.

• Journal of the Ergonomics Society of Korea
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• v.28 no.2
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• pp.27-34
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• 2009

The purpose of this study was to evaluate aging (young and old), gender (male and female), and handle shape effects on grip force, finger force, and subjective comfort. Four handle shapes of A, D, I, and V were implemented by a multi-finger force measurement (MFFM) system which was developed to measure every finger force with different grip spans. Forty young (20 males and 20 females) and forty old (20 males and 20 females) subjects participated in twelve gripping tasks and rated their comfort for all handles using a 5-point scale. Grip forces were calculating by summation of all four forces of the index, middle, ring and little fingers. Results showed that young males (283.2N) had larger gripping force than old males (235.6N), while young females (151.4N) had lower force than old females (153.6N). Young subjects exerted the largest gripping force with D-shape due to large contribution of the index and middle fingers and the smallest with A-shape; however, old subjects exerted the largest with I-shape and the smallest with V-shape due to small contribution of the ring and little fingers. As expected, the middle finger had the largest finger force and the little finger had the smallest. The fraction of contribution of index and ring fingers to grip force differed among age groups. Interestingly, young subjects provided larger index finger force than ring finger force, whereas old subjects showed that larger ring finger forces than index finger force in the griping tasks. In the relationship between performance and subjective comfort, I-shape exerting the largest grip force had less comfort than D-shape producing the second largest grip force. The findings of this study can provide guidelines on designing hand tool handle to obtain better performance as well as users' comfort.

• Animal cells and systems
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• v.1 no.1
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• pp.53-61
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• 1997

Seasonal variation of the population structure and the reproductive pattern of the Korean striped field mouse, Apodemus agrarius, were investigated. High capture ratios in juveniles, young adult, and old adult mice were found during the period from October to November, from November to March, and from May to September, respectively, and extremely low capture ratios of old adults during the period from November to February were characteristic. It seemed that the young adults that survived during the winter might become older by summer and have been counted as the old adults. The breeding in the mice began earlier in males (from mid February or early March to late October) than in females (from mid March to late October), having a peak in August and September, and both the male and female mice weighing more than 20 g generally reached sexual maturation in general. In the breeding season, both young and old adult males had large testes with enlarged seminiferous tubules filled with numerous germ and Sertoli cells, and expanded caudal epididymides with a vast number of spermatozoa; the females had many Graafian follicles and corpora lutea in large ovaries, and developed uterine glands in the thick endometria. The lower ratios of the testis weight to the body weight in July and August in 1994 compared to 1995 seemed due to the extreme drought and considerably higher temperature in 1994, but the decrease in the ratio in mid-summer, only in the old mice, in both years might be explained partially by aging.