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A Case of Urinary Tract Infection Treated with Gagamyookmijihwang-tang(Jia-Jian-Liu-Wei-De-Huang-Tang) in Stroke Patient (중풍환자의 급성요도염에 대하여 단독 한방처방 투여로 치료한 1례)

  • Han, Jin-An;Cho, Ki-Ho;Kim, Jung-Jin
    • The Journal of Internal Korean Medicine
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    • v.23 no.2
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    • pp.286-291
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    • 2002
  • Urinary tract infection(UTI) is one of the common complications in stroke patients. As it has negative effect on the recovery of stroke, it should be cured out immediately. But antibiotics might cause some adverse reactions such as diarrhea, eruption, anorexia, nausea and vomiting. so there have been several reports about treating urinary tract infection with Traditional Korean Medication. We treated a 54-year-old male patient with cerebral hemorrhage, who had had neurogenic bladder after stroke and had been urinated by intermittent catheterization. About 10 days later, he could void by himself without catheter, but showing the symptoms of UTI; Voiding pain, hematuria and yellowish pus. The pus culture grew Staphylococcus spp., which was resistant to most of antibiotics except vancomycin and teicoplanin. Based on accompanying symptoms of intermittent dizziness, headache, insomnia, nocturnal sweating, weak pulse, red tongue and urinary problem, we differentiated him as the deficiency of Yin of the Kidney[腎陰虛] and treated with Gagamyookmijihwang-tang (Jia-Jian-Liu-Wei-De- Huang-Tang), which improved his urinary symptoms and other general conditions without any side effect. In next follow-up culture, there was no pathogen. We conclude that Traditional Korean Medicine based on differentiation is useful in the treatment of urinary tract infection.

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First Report of Anthracnose Caused by Colletotrichum acutatum on Begonia (Begonia semperflorens Link.) Nurseries

  • Park, Jong-Kyu;Kim, Gyoung-Hee;Min, Gyung-Mi;Park, Hee-Jin;Hur, Jae-Seoun;Kang, Beum-Kwan;Kim, Heung-Tae;Choi, Woo-Bong;Koh, Young-Jin
    • The Plant Pathology Journal
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    • v.22 no.1
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    • pp.7-10
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    • 2006
  • Anthracnose severely occurred on begonia (Begonia semperflorens Link.) nurseries in Gyeongju, Gyeongbuk in July, 2004. More than $80\%$ of begonia seedlings were diseased in the greenhouse surveyed and diseased leaves per plant were $12.1\%$ in average. Yellowish spots occurred on the leaves of begonia as initial symptoms, and they coalesced irregularly to form large brown pleomorphic lesions. Severely infected leaves were defoliated, resulting in abnormal growth of the entire plant. Colletotrichum sp. was repeatedly isolated from the diseased plants and was identified as Colletotrichum acutatum on the basis of the mycological characteristics on potato dextrose agar and RAPD analysis. Pathogenicity of the fungus was also confirmed by artificial inoculation on healthy plants. The optimum temperature for mycelial growth of C. acutatum was around $25^{\circ}C$. The fungus was sensitive to azoxystrobin, bitertanol, diethofencarb-carbendazim, difenoconazole and tebuconazole. This is the first report on the anthracnose of begonia caused by C. acutatum in Korea.

Occurrence of Apple scar viroid-Korean strain (ASSVd-K) in Apples Cultivated in Korea

  • Lee, Ju-Hee;Park, Jean-Kyung;Lee, Dong-Hyuk;Uhm, Jae-Youl;Ghim, Sa-Youl;Lee, Jai-Youl
    • The Plant Pathology Journal
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    • v.17 no.5
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    • pp.300-304
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    • 2001
  • Apple is the most economically important fruit in Korea. The suspected viroid disease of dapple apple was found in apple fruits cultivated in Kyungpook province. Symptoms begin in mid-July as small circular spots, which stand out against the background color on the young fruit. Dappling of the fruit becomes more intense and easier to detect as the fruit approaches maturity; the affected spots remain yellowish as the fruit matures. no leaf or bark syndromes have been associated with this disease. The infected fruits are downgraded considerably during quality grading. The low molecular weight RNA containing viroid RNA molecules were extracted from the peels of the apples with dapple symptoms. The RNA molecules were extracted from the apples using Qiagen column chromatography. The purified RNAs were used for the synthesis of cDNA with RT-PCR. The PCR products were then ligated into a pGEM-T Easy vector, cloned and sequenced. The sequence of the viroid RNA molecule shows 331 nucleotides with one base difference ("G" insertion between the position of 133 and 134) compared with that of the Apple scar skin viroid (ASSVd) reported by Hashimoto and Koganezawa in Japan. This is the first report on the occurrence of the ASSVd in apple trees cultivated in Korea, as well as the identification of a new Korean strain of the ASSVd.the ASSVd.

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Sclerotium blight of Neofinetia falcata Caused by Sclerotium rolfsii in Korea (Sclerotium rolfsii에 의한 소엽풍란 흰비단병)

  • Han, Kyung-Sook;Lee, Seong-Chan;Han, You-Kyoung;Kim, Su;Kim, Dong-Hwi
    • Research in Plant Disease
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    • v.16 no.3
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    • pp.320-322
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    • 2010
  • The Sclerotium blight was found on Neofinetia falcata at Yong-in city, Gyenggi-do, Korea. The symptom occurred low leaves yellowish and wilt of a whole plant. Severely infected plants were blighted and dies eventually. White mycelial mats appeared on the surface of basal stem and bulbs and the sclerotia were formed on stems, roots, and sphagnum moss. The sclerotia were spherical in shape, 1~3 mm in size and white to brown in color. The optimum temperature for the growth and sclerotia formation was $25{\sim}30^{\circ}C$ on PDA. On the pathogenicity test, the first symptom was appeared 5 days after inoculation and development to severe stem rot and blight. The causal fungus was identified as Sclerotium rolfsii and we suggested to call that the new Sclerotium blight on Neofinetia falcata caused by Sclerotium rolfsii in Korea.

The First Case of Capillaria hepatica Infection in a Nutria (Myocastor coypus) in Korea

  • Park, Jae-Hak;Novilla, Meliton N.;Song, Juha;Kim, Kyung-Sul;Chang, Seo-Na;Han, Ju-Hee;Lee, Byung Hee;Lee, Do-Hun;Kim, Hyun-Mac;Kim, Young-Ha;Youn, Hee-Jeong;Kil, Jihyon
    • Parasites, Hosts and Diseases
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    • v.52 no.5
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    • pp.527-529
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    • 2014
  • This study reports the first case of Capillaria hepatica infection in a nutria in Korea. Ten nutrias, captured near the Nakdong River, were submitted to our laboratory for necropsy. White-yellowish nodules were found in the liver of 1 of the nutrias at necropsy. Histologically, the lesions were granulomatous, and infiltrations of lipid-laden macrophages, eosinophils, and several multinucleated giant cells were observed. The lesions consisted of numerous eggs and necrotic hepatocytes. The eggs were lemon-shaped and had polar plugs at the ends of both long sides. The eggs were morphologically identified as those of C. hepatica. Worldwide, C. hepatica infection in nutrias is very rare. Nutrias are a kind of livestock, as well as wildlife; therefore, an epidemiological study for parasitic infections needs to be conducted.

Ossifying Epulis in a Thoroughbred Foal (더러브렛 망아지에서 발생한 골화성 치은종)

  • Kim, Joon-Gyu;Mun, Seong-Hwan;Ko, Kyu-Ryeon;Kim, Jae-Hoon
    • Journal of Veterinary Clinics
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    • v.31 no.2
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    • pp.159-162
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    • 2014
  • A 4-month-old female thoroughbred foal was presented with large mass on mandibular gingiva. The enlarged mass was firm and yellowish pink in color, and occupied the whole mandibular arcade. The filly could not close her mouth with her lips. Radiographs showed radioopaque mass under the mandible. The mass was surgically excised from mandible. Histopathologically, gingival mass was characterized by hyperplastic gingival epithelium, well vascularized collagenous stroma and large area of bony tissues. Based on the gross and histopathologic findings, this case was diagnosed as ossifying epulis in the mandibular gingiva. This is the first report of ossifying epulis in a thoroughbred horse in Korea.

Pathogenecity on experimentally infected dogs with Babesia gibsoni (Babesia gibsoni의 실험적 감염 개에 대한 병원성)

  • Suh, Myung-deuk;Chung, Mi-ra
    • Korean Journal of Veterinary Research
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    • v.40 no.3
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    • pp.587-599
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    • 2000
  • This study was conducted to observe the severity of the disease and pathogenecity of Babesia gibsoni parasite on the splenectomized dogs(SPD) and nonsplenectomized(intact) dogs (NSPD) experimentally infected with B gibsoni. The average prepatent period was 4 days in the SPD and 8 days in the NSPD, respectively. Peak parasitaemia(PE) ranged from 26% to 34% of erythrocytes infected in the SPD and from 4% to 5% in the NSPD. Latent parasitaemia was still detectable 40 days as low as under 1.0% of erythrocytes infected after the initial parasitaemia in the SPD. Blood packed cell volume(PCV) decreased to as little as 6.4% to 6.9% in the SPD. The clinical signs were mild fever and anemia in the NSPD, remissions and exacervations of temperature, intermittent or spike-like increases of temperature, progressive polychromatophilic macrocytic anemia with anisocytosis, icterus, marked loss of appetite, rarely haemoglobinuria, and deep brown-yellowish urine in the SPD. Gross pathologic changes mainly involved slightly enlargement of liver and spleen in the NSPD and marked enlargement of liver in the SPD. Anatomic changes associated with the disease included diffuse periportal and centrilobular hephatitis, and membranoproliferative glomerulonephritis. Hyaline droplets, resulting protein metabolic alterations, were found in the convoluted ephithelium of the kidney. The density of lymphocytes within the liver sinusoids was markedly increased. Aggregates of large monocytes and macrophages were demonstrated in the centrilobular veins of the liver. The density of these cells in the centrilobular veins were greatest in the SPD. The forms of B gibsoni parasite found in the acute stage of SPD were large signet ring form, small signet ring form, pyriform, elongated form, comma form, head-phone form, oval form, peared form, racket-like form, amoeboid form, triangle form, quartered form, dot form, band form and multiple, and rosette form, et al. The severity of the disease and pathogenecity of B gibsoni parasite were mild in the NSPD but fatal in the SPD.

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Studies on the necrotic enteritis of chicken in Korea (국내(國內) 닭의 괴사성 장염 발생에 관한 연구)

  • Park, Kyoung-yoon;Jung, Sung-dae;Yeh, Jae-gil;Seo, Il-bok
    • Korean Journal of Veterinary Research
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    • v.34 no.3
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    • pp.593-599
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    • 1994
  • This study was carried out to investigate the necrotic enteritis of chicken in Korea. Epidemiological, pathological and microbiological examination were done on 12 naturally occurred cases of necrotic enteritis of chicken. And the susceptibility of isolated bacteria to antimicrobial agents was also examined. The results obtained were as follows; 1. The Clostridium perfringens infection, necrotic enteritis of chicken, occurred in the chickens mainly raised in floor pens. Necrotic enteritis of chicken was occurred coincidently with coccidiosis and Gumboro disease frequently. And several cases were recurred at 2-3 weeks after recovery. 2. Clinical signs of the infected chickens were depression, decreased appetite, reluctance to move, diarrhea, ruffled feathers and acute death within several hours. 3. The characteristic biochemical properties of isolates were 2-band hemolysis, no motility, positive reaction of reverse CAMP test and the formation of LV precipitate in egg yolk medium. 4. Gross lesions of the infected chickens were distention of intestine with gas, thickened mucosa and formation of thick pseudomembrane in intestine. Livers were friable with yellowish brown color and, in some case, showed demarcated necrotic foci. 5. Histopathological findings of the infected chickens were severe necrosis of the intestinal mucosa and attachment of numerous large bacilli to the mucosal surface of necrotic villi. In liver, necrosis of liver tissue and numerous large bacilli in the necrotic foci were also observed. 6. In susceptibility test to antimicrobial agents, 12 isolates of Clostridium perfringens were highly sensitive to ampicillin, baytril, cephalothin and penicillin.

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Mineralogical Characteristics and Origins of Smectite in the Marine Sediment around South Shetland Islands, Antarctica (남극 사우스셰틀란드 해양퇴적물내 스멕타이트의 광물학적 특성과 기원)

  • 정기영;윤호일
    • Journal of the Mineralogical Society of Korea
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    • v.15 no.1
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    • pp.22-32
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    • 2002
  • Mineral composition and chemistry of the clay minerals in the three cores from the continental shelves of South Shetland Islands (NCS09) and Anberse Island (GC98-2), and from the fjord of King George Island (A10-01) were determined by X-ray diffraction and electron microprobe analysis in search of the distributions and origin of the clay minerals in the Antarctic marine sediments. Smectite content is relatively high in NCS09 regardless of core depths (av. 8.3%), but low in GC98-2 (1.1%). In Al0-01, smectite content is higher in the upper section than in the lower section. Kaolinite was not detected from all the cores in this study Yellow to yellowish green clay granules were commonly scattered in the sediments of NCS09 cores. The clays contain 16.97% and 2.53% $Fe_2$$O_3$$K_2$O. Average structural formula of the clay indicates ferrian beidellite . The (Fe, K)-rich smectite of NSC09 must have been derived from relatively young basaltic volcanics altered by reaction with seawater near Shetland Islands by glacial erosion or eolian process related to volcanic eruption. GC98-2 nearer to Antarctic continent is very low in smectite content. In A10-01, the lower diamicton was deposited from the glacial erosion of smectite-free ancient volcanics in the interior of King George Island, while the upper section was derived from the smectite-bearing terrestrial debris and eolian materials after retreat of glaciers in Marian Cove and ice cover in Barton Peninsula. Thehigh K contents of smectites suggest the interstratification of illite and smectite layers, which might be observed by future TEM lattice fringe imaging.

Lipase-Catalyzed Synthesis of Structured Lipids with Capric and Conjugated Linoleic Acid in a Stirred-Batch Type Reactor (대두유로부터 Lipase를 이용한 재구성 지질의 합성 및 특성)

  • 신정아;이기택
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.7
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    • pp.1175-1179
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    • 2004
  • Structured lipid (SL) was produced from soybean oil with molar ratio of 1:2:2 (soybean oil:capric acid:CLA) using Chirazyme L-2 lipase (4% by weight of total substrates). The reaction was conducted for 24 hr at 55$^{\circ}C$ in a 1 L stirred-batch type reactor. SL-soybean oil contained 4.9 mol% capric acid and 4.1 mol% CLA, respectively. Iodine value of SL-soybean oil was reduced than that of soybean oil due to the incorporated capric acids. Tocopherol content in SL-soybean oil was 18.2 mg/l00 g. SL-soybean oil appeared more yellowish color than soybean oil. Reverse-phase HPLC showed that SL-triacylglycerol species containing capric acid consisted of about 12.6 area%.