• 제목/요약/키워드: xHDL

검색결과 74건 처리시간 0.019초

리프팅 기반의 고속 정수 웨이블릿 변환의 효율적인 구현 구조 (An Efficient Implementation Architecture for Lifting Based High Speed Integer Wavelet Transform)

  • 김석준;장영조
    • 대한임베디드공학회논문지
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    • 제7권4호
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    • pp.173-179
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    • 2012
  • In this paper, we propose an efficient architecture for 2D IWT using an existing 1D IWT. Lifting based IWT is the architecture of which a multiplier is replaced by adders and shift registers. The structure is relatively simple and modular. The proposed architecture to process an image size with 256x256 pixels consists of 16 adders, 8 shift registers, and some memories. By processing two rows at the same time, 2D sub-band coefficients can be calculated immediately after 1D sub-band coefficients have been processed. The architecture is designed so that each image can be inputted consecutively. The number of adders and shift registers is increased by twice comparing the existing architecture, but the memory size and the execution time are decreased by half. The proposed architecture is implemented using Verilog-HDL and simulated using iSim. It is synthesized and demonstrated at ISE for xc5vlx330 in RPS3K board.

Vitamin C가 방사선과 Aflatoxin B1을 투여한 흰쥐의 혈청과 간장의 지질성분 및 지방산 조성에 미치는 영향 (The Effects of Vitamin C on Lipid Contents and Fatty Acid Compositions of Serum and Liver in Rats Treated with Radiation or Aflatoxin B1)

  • 강진순;김소영;김희숙;조흥래;채규영;정덕화
    • 한국식품영양과학회지
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    • 제36권2호
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    • pp.163-173
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    • 2007
  • Aflatoxin은 Aspergillus속 곰팡이로부터 생성되며 사람에게 있어서 간독성 및 간암을 유발하는 잠재력을 가진 곰팡이 독소이며, 지질과산화 반응은 aflatoxin $B_1$에 의한 세포 산화적 손상 시 발생하는 주요 현상 중의 하나이다. 방사선은 수술, 항암약물요법과 더불어 임상 시 중요한 치료방법이나, 정상세포에 방사선을 조사하였을 때 반응성이 높은 활성산소와 과산화라디칼$(OH{\cdot})$을 생성하여 세포막의 불포화지방산을 지질과산화물로 변성시켜 세포 산화적 손상을 일으킨다. 따라서 본 연구의 목적은 aflatoxin $B_1$과 방사선조사 후 유도된 간과 혈청의 지질성분 및 지방산 조성에 미치는 vitamin C의 영향을 조사하기 위해 수행되었다. X-ray 조사는 실험기간 내 단 1회로 실험사육기간 첫 일에 조사하였고 X-ray 조사 후 vitamin C를 투여하였으며 vitamin C 투여 1시간 후 $AFB_1$을 투여하였다. Vitamin C와 $AFB_1$은 모두 복강투여로 실험 사육 첫 일부터 1회 시작하여 3일에 한번씩, 5회 반복 투였으며 실험동물 사육기간은 총 15일로 하였다. 혈청 총콜레스테롤 농도는 $1\sim5$군에서 유의적인 차이를 볼 수 없었는데 방사선과 $AFB_1$을 함께 처리한 6군에서는 $130.37{\pm}9.14mg/dL$로서 전군에서 가장 높은 수치를 나타낸 반면 6군에 vitamin C를 혼합 투여한 7군에서는 $90.23{\pm}6.15mg/dL$로서 가장 낮았으며 이는 중성지질과 유사한 경향이었다. 또한 간장의 총콜레스테롤과 유리 콜레스테롤도 이와 유사한 경향이었다. HDL 농도는 방사선과 $AFB_1$을 함께 처리한 것에 vitamin C를 혼합 투여한 7군이 $59.57{\pm}9.56mg/dL$로서 p<0.01 수준에서 현저히 증가하였다. 혈청의 인지질과 콜레스테롤 에스테르의 지방산 조성에서 vitamin C를 혼합 투여한 3,5,7군에서 PUFA 함량이 증가한 반면, SFA 함량은 감소하여 P/S 비율, n-3P/n-6P 비율은 증가하는 경향이었으며 이는 간장의 인지질, 콜레스테롤 에스테르, 총 지질의 지방산조성에서도 같은 경향을 볼 수 있었다.

효율적인 클리핑 기능을 갖는 3차원 그래픽 파이프라인 구조 (A 3D graphic pipelines with an efficient clipping algorithm)

  • 이찬호
    • 대한전자공학회논문지SD
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    • 제45권8호
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    • pp.61-66
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    • 2008
  • 최근 모바일 기기에 3차원 그래픽 디지털 콘텐츠들이 증가함에 따라 휴대용 기기에 적합한 3차원 그래픽 가속기의 연구와 설계는 점점 중요한 이슈가 되고 있다. 본 논문에서는 저전력 3차원 그래픽 파이프라인에 적합한 효율적인 클리핑 구조를 제안한다. 많은 연산 사이클과 연산기를 필요로 하는 클리핑 연산을 두 단계로 나누어서 기하변환 엔진에서는 컬링 정렬(cull and sort) 유닛으로 구현하고, 실질적인 클리핑은 스캔 변환(scan conversion)에서 구현한다. 즉, 스캔 변환 처리기를 구성하고 있는 변처리 (edge walk) 유닛에서 Y축 클리핑을 함께 수행하고 스팬처리 (span processing) 유닛에서 X축과 Z축 클리핑을 함께 수행한다. 제안하는 기하 변환 엔진의 컬링 정렬 유닛은 기존 클리핑 유닛에 비해 면적과 동작 사이클이 크게 줄었고 스캔 변환 처리기의 면적은 거의 증가하지 않아 전반적으로 동작 속도 및 동작 효율을 높였다. 제안하는 클리핑 구조를 적용한 3차원 그래픽 가속기는 Verilog-HDL을 이용하여 설계하고 FPGA를 이용하여 검증하였다.

Effects of Dietary Olive Oil on Growth Performance, Carcass Parameters, Serum Characteristics, and Fatty Acid Composition of Breast and Drumstick Meat in Broilers

  • Zhang, Z.F.;Zhou, T.X.;Kim, I.H.
    • Asian-Australasian Journal of Animal Sciences
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    • 제26권3호
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    • pp.416-422
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    • 2013
  • This experiment was conducted to evaluate the effects of dietary olive oil on growth performance, carcass parameters, serum characteristics, and fatty acid composition of breast and drumstick meat in broiler chickens. A total of 480 broilers were randomly allotted into three dietary treatments, including T (basal diet, 5% tallow), O1 (2% olive oil+3% tallow), and O2 (5% olive oil). During d 0 to 21, broilers fed the diet supplemented with 5% olive oil showed lower (p<0.05) body weight gain (BWG) and feed intake (FI) compared with those fed the T diet. Serum triglyceride concentration was reduced (p<0.05), while high density lipoprotein (HDL)-cholesterol concentration was increased (p<0.05) in the O2 treatment group compared with the T and O1 treatment groups. The addition of olive oil to the diets induced a reduction (p<0.05) in the total saturated fatty acid (SFA) contents in breast and drumstick meat, and increased (p<0.05) the total unsaturated fatty acid (USFA) contents and USFA/SFA ratios. In conclusion, a diet with 5% olive oil could decrease BWG and FI of broilers during the starter period (wk 0 to 3), and cause an increase in the serum HDL-cholesterol level, while decreasing the serum triglyceride concentration. Furthermore, USFA level and USFA/SFA ratios in breast and drumstick meat were increased by dietary supplementation of 2 or 5% olive oil.

중년여성의 혈중 지질농도, 신체증상, 헤모글로빈에 미치는 단전호흡운동과 걷기운동의 효과 비교 (Comparison of the Effects of Danjeon Breathing and Walking to Blood Lipids, Physical Symptoms and Hemoglobin in Middle Aged Women)

  • 현경선
    • 동서간호학연구지
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    • 제10권1호
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    • pp.41-52
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    • 2004
  • Purpose: The purpose of this research was to compare the effects of Danjeon Breathing exercise and walking exercise on blood lipids, physical symptoms and hemoglobin of middle-aged women to determine which of these two exercises was more beneficial. Methods: The Danjeon breathing exercise group(20) took health management counseling and performed an eighty-minute Danjeon breathing exercise three times a week for 12 weeks while the walking exercise group(25) took health management counseling and performed a walking exercise seven hours per week for 12 weeks. The control group(20) received only health management counseling. The groups were homogeneous on age, religion, marital status, education, profession, monthly income per household, menopause, smoking, drinking, fat intake and cholesterol intake. Likewise, the groups were homogeneous on total cholesterol, HDL-cholesterol,atherogenic index, hemoglobin and physical symptoms. The collected data were analyzed by using the SPSS PC program and $x^2$-test, ANOVA, repeated measures of ANOVA and LSD. Results: 1. Total cholesterol of the Danjeon breathing exercise group and the walking exercise group were lower than that of the control group. 2. HDL- cholesterol of the Danjeon breathing exercise group and the walking exercise group were not higher than that of the control group. 3. Atherogenic index of the Danjeon breathing exercise group was lower than that of the control group, but atherogenic index of the walking exercise group was not lower than that of the control group. 4. Hemoglobin of the Danjeon breathing exercise group and the walking exercise group were not higher than that of the control group. 5. Physical symptom score of the Danjeon breathing exercise group was lower than those of the walking exercise group and the control group, but Physical symptom score of the walking exercise group was not lower than that of the control group. Conclusion: Danjeon breathing exercise and walking exercise are effective for decreasing total cholesterol of middle-aged women. Danjeon breathing exercise is more effective for decreasing atherogenic index and physical symptoms of middle-aged women than walking exercise.

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대사증후군 환자에게 적용한 12주간의 타이치 운동이 자율신경계 활성도와 대사증후군 위험요인에 미치는 효과에 대한 예비 실험연구 (A Pilot Study Examining the Effects of 12-week Tai chi Exercise on the Activity of Autonomic Nervous System and Risk Factors of Metabolic Syndrome in Patients with Metabolic Syndrome)

  • 공경란;이은남;황현주
    • 근관절건강학회지
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    • 제23권1호
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    • pp.1-8
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    • 2016
  • Purpose: This study was to examine the effects of 12-week Tai Chi exercise on the autonomic nervous system activity and risk factors of metabolic syndrome in patients with metabolic syndrome. Methods: A single group pre-posttest was used. Subjects were 16 participants aged 51~71 years with metabolic syndrome. All of the subjects were met the criteria of the National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III). The Tai Chi exercise consisted of 19 movements from Yang and Sun styles provided twice a week for 3 months. Metabolic syndrome risk factors including waist circumference, blood pressure, glucose, triglyceride, high density lipoprotein cholesterol (HDL-cholesterol) were measured. A heart rate variability device was used to measure the activity of autonomic nervous system. Results: After 12-week Tai Chi exercise, systolic pressure, waist circumference, and HDL-cholesterol improved significantly. Tai Chi exercise had no effect on the autonomic nervous system activity. Conclusion: The 12-week Tai Chi exercise was partially effective in managing risk factors of metabolic syndrome. A larger study with longer period to improve the autonomic nervous system activity in patients with metabolic syndrome is needed.

Effects of Dietary Dihydropyridine Supplementation on Laying Performance and Fat Metabolism of Laying Hens

  • Zou, X.T.;Xu, Z.R.;Zhu, J.L.;Fang, X.J.;Jiang, J.F.
    • Asian-Australasian Journal of Animal Sciences
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    • 제20권10호
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    • pp.1606-1611
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    • 2007
  • The experiment was conducted to investigate the effects of dihydropyridine on laying performance and fat metabolism of laying hens. Five hundred and forty laying hens, 40 weeks old, were randomly allotted to three groups, each of which included four replicates of 45 hens. The groups were given a basal corn-soybean meal diet supplemented with 0, 150 mg/kg and 300 mg/kg dihydropyridine. Results showed that compared with the control group (0 mg/kg dihydropyridine), supplements of 150 and 300 mg/kg dihydropyridine increased egg production rate by 9.39% (p<0.01) and 12.97% (p<0.01), increased mean egg weight by 3% (p>0.05) and 4.8% (p>0.05), and improved feed efficiency by 9.54% (p<0.05) and 7.25% (p<0.05), respectively; The addition of 150 and 300 mg/kg dihydropyridine decreased percentage of abdominal fat by 35.4% (p<0.05) and 46.9% (p<0.05), decreased liver fat content by 32.4% (p<0.05) and 10.5% (p<0.05), increased HSL activity of abdominal fat by 39.64% (p<0.05) and 48.48% (p<0.05), increased HSL activity of liver by 9.4% (p>0.05) and 47.34% (p<0.05) and increased the content of cAMP in adenohypophysis by 14.67% (p<0.05) and 10.91% (p<0.05), respectively; The inclusion of 150 mg/kg dihydropyridine increased liver superoxide dismutase activity by 69.61% (p<0.05), and increased hepatic apoB concentration by 53.96% (p<0.05); The supplementation of 150 or 300 mg/kg dihydropyridine decreased malondialdehyde concentration of hepatic mitochondria by 30.90% (p<0.01) and 10.39% (p<0.05), respectively; Supplemented dihydropyridine had no significant effects on TG, Ch HDL-C and VLDL-C concentrations in serum; addition of 150 or 300 mg/kg dihydropyridine increased T3 levels in serum by 15.34% (p<0.05) and 11.88% (p<0.05) and decreased insulin concentration by 40.44% (p<0.05) and 54.37% (p<0.05), respectively. The results demonstrated that adding dihydropyridine had the tendency of improving very low density lipoprotein receptor (VLDLR) content in the ovary. It was concluded that dihydropyridine could improve laying performance and regulate the fat metabolism of laying hens and that 150 mg/kg dihydropyridine is the optimum dose for laying birds in practical conditions.

Deletion of the Lmna Gene Induces Growth Delay and Serum Biochemical Changes in C57BL/6 Mice

  • Ruan, J.;Liu, X.G.;Zheng, H.L.;Li, J.B.;Xiong, X.D.;Zhang, C.L.;Luo, C.Y.;Zhou, Z.J.;Shi, Q.;Weng, Y.G.
    • Asian-Australasian Journal of Animal Sciences
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    • 제27권1호
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    • pp.123-130
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    • 2014
  • The A-type lamin deficient mouse line ($Lmna^{-/-}$) has become one of the most frequently used models for providing insights into many different aspects of A-type lamin function. To elucidate the function of Lmna in the growth and metabolism of mice, tissue growth and blood biochemistry were monitored in Lmna-deficient mice, heterozygous ($Lmna^{+/-}$) and wide-type ($Lmna^{+/+}$) backcrossed to C57BL/6 background. At 4 weeks after birth, the weight of various organs of the $Lmna^{-/-}$, $Lmna^{+/-}$ and $Lmna^{+/+}$ mice was measured. A panel of biochemical analyses consisting of 15 serological tests was examined. The results showed that Lmna deficient mice had significantly decreased body weight and increased the ratio of organ to body weight in most of tissues. Compared with $Lmna^{+/+}$ and $Lmna^{+/-}$ mice, $Lmna^{-/-}$ mice exhibited lower levels of ALP (alkaline phosphatase), Chol (cholesterol), CR (creatinine), GLU (glucose), HDL (high-density lipoprotein cholesterol) and higher levels of ALT (alanine aminotransferase) (p<0.05). $Lmna^{-/-}$ mice displayed higher AST (aspartate aminotransferase) values and lower LDL (lowdensity lipoprotein cholesterol), CK-MB (creatine kinase-MB) levels than $Lmna^{+/+}$ mice (p<0.05). There were no significant differences among the three groups of mice with respect to BUN (blood urea nitrogen), CK (creatine kinase), Cyc C (cystatin C), TP (total protein), TG (triacylglycerols) and UA (uric acid) levels (p>0.05). These changes of serological parameters may provide an experimental basis for the elucidation of Lmna gene functions.

FXRα Down-Regulates LXRα Signaling at the CETP Promoter via a Common Element

  • Park, Sung-Soo;Choi, Hojung;Kim, Seung-Jin;Kim, Ok Jin;Chae, Kwon-Seok;Kim, Eungseok
    • Molecules and Cells
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    • 제26권4호
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    • pp.409-414
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    • 2008
  • The cholesteryl ester transfer protein (CETP), a key player in cholesterol metabolism, has been shown to promote the transfer of triglycerides from very low density lipoprotein (VLDL) and low density lipoprotein (LDL) to high density lipoprotein (HDL) in exchange for cholesterol ester. Here we demonstrate that farnesoid X receptor ${\alpha}$ ($FXR{\alpha}$; NR1H4) down-regulates CETP expression in HepG2 cells. A $FXR{\alpha}$ ligand, chenodeoxycholic acid (CDCA), suppressed basal mRNA levels of the CETP gene in HepG2 cells in a dose-dependent manner. Using gel shift and chromatin immunoprecipitation (ChIP) assays, we found that $FXR{\alpha}$ could bind to the liver X receptor ${\alpha}$ ( $LXR{\alpha}$; NR1H3) binding site (LXRE; DR4RE) located within the CETP 5' promoter region. $FXR{\alpha}$ suppressed $LXR{\alpha}$-induced DR4RE-luciferase activity and this effect was mediated by a binding competition between $FXR{\alpha}$ and $LXR{\alpha}$ for DR4RE. Furthermore, the addition of CDCA together with a $LXR{\alpha}$ ligand, GW3965, to HepG2 cells was shown to substantially decrease mRNA levels of hepatic CETP gene, which is typically induced by GW3965. Together, our data demonstrate that $FXR{\alpha}$ down-regulates CETP gene expression via binding to the DR4RE sequence within the CETP 5' promoter and this $FXR{\alpha}$ binding is essential for $FXR{\alpha}$ inhibition of $LXR{\alpha}$-induced CETP expression.

고지혈증 수진자를 위한 전자메일 교육 프로그램 개발 및 적용효과 (Development of E-Mail Education for Hyperlipidemia Health Check-up and Application Effects)

  • 한상숙;김선희
    • 대한간호학회지
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    • 제36권7호
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    • pp.1154-1163
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    • 2006
  • Purpose: This study was to monitor the effects of forming desirable eating and exercise habits and change the blood lipid levels by developing and applying E-Mail educational programs for a hyperlipidemia health check-up. Method: The research design used a nonequivalent control group pre-post test. Ninety-nine subjects (Exp.=50, Cont.=49) were selected randomly and the male subjects agreed to a hyperlipidemia health check-up at a comprehensive medical screening center. This study verified validity and reliability through factor analysis on a life habit measurement tool. The data was analyzed with SPSS win 12.0 using an $X^2-test$, t-test, ANOVA and ANCOVA. Result: Eatingand exercise habit scores of the experimental group which were educated through E-Mails changed considerably more than that of the control group which was not educated. Total-cholesterol and LDL-cholesterol in the experimental group was considerably lower than that in the control group, but HDL-cholesterol increased considerably Triglycerides, however, didn't show change. Conclusion: An E-Mail educational program may be applied as a hyperlipldemia health check-up nursing intervention strategy.