• 제목/요약/키워드: working gas

검색결과 707건 처리시간 0.032초

Korean Red Ginseng extract attenuates alcohol-induced addictive responses and cognitive impairments by alleviating neuroinflammation

  • Hee Jin Kim;Min Yeong Lee;Gyu Ri Kim;Hyun Jun Lee;Leandro Val Sayson;Darlene Mae D. Ortiz;Jae Hoon Cheong;Mikyung Kim
    • Journal of Ginseng Research
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    • 제47권4호
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    • pp.583-592
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    • 2023
  • Background: Alcohol is one of the most commonly used psychoactive drugs. Due to its addictive characteristics, many people struggle with the side effects of alcohol. Korean Red Ginseng (KRG) is a traditional herbal medicine that is widely used to treat various health problems. However, the effects and mechanisms of KRG in alcohol-induced responses remain unclear. Therefore, the purpose of this study was to investigate the effects of KRG in alcohol-induced responses. Methods: We investigated two aspects: alcohol-induced addictive responses and spatial working memory impairments. To determine the effects of KRG in alcohol-induced addictive responses, we performed conditioned place preference tests and withdrawal symptom observations. To assess the effects of KRG in alcohol-induced spatial working memory impairment, Y-maze, Barnes maze, and novel object recognition tests were performed using mice after repeated alcohol and KRG exposure. To investigate the potential mechanism of KRG activity, gas chromatography-mass spectrometry and western blot analysis were performed. Results: KRG-treated mice showed dose-dependent restoration of impaired spatial working memory following repeated alcohol exposure. Furthermore, withdrawal symptoms to alcohol were reduced in mice treated with KRG and alcohol. The PKA-CREB signaling pathway was activated after alcohol administration, which was reduced by KRG. However, the levels of inflammatory cytokines were increased by alcohol and decreased by KRG. Conclusion: Taken together, KRG may alleviate alcohol-induced spatial working memory impairments and addictive responses through anti-neuroinflammatory activity rather than through the PKA-CREB signaling pathway.

가스분무성형 Cu-5Ni-10Sn 합금의 미세조직 및 시효강화 (Microstructural Feature and Aging Characteristics of Spray-Formed Cu-5Ni-10Sn Alloy)

  • 노대균;강희수;백경호
    • 한국분말재료학회지
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    • 제19권4호
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    • pp.317-321
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    • 2012
  • In this study, Cu-5Ni-10Sn(wt%) spinodal alloy was manufactured by gas atomization spray forming, and the microstructural features and mechanical properties of Cu-5Ni-10Sn alloy have been investigated during homogenization, cold working and age-hardening. The spray formed Cu-5Ni-10Sn alloy consisted of an equiaxed microstructure with a mixture of solid solution ${\alpha}$-(CuNiSn) grains and lamellar-structure grains. Homogenization at $800^{\circ}C$ and subsequent rapid quenching formed a uniform solid solution ${\alpha}$-(CuNiSn) phase. Direct aging at $350^{\circ}C$ from the homogenized Cu-5Ni-10Sn alloy promoted the precipitation of finely distributed ${\gamma}$' or ${\gamma}-(Cu,Ni)_3Sn$ phase throughout the matrix, resulting in a significant increase in microhardness and tensile strength. Cold working prior to aging was effective in strengthening Cu-5Ni-10Sn alloy, which gave rise to a maximum tensile strength of 1165 MPa. Subsequent aging treatment slightly reduced the tensile strength to 1000-1100 MPa due to annealing effects.

회전형 히트파이프 열교환기의 작동유체 귀환력 해석 및 열전달특성에 관한 연구 (The Returning Force Analysis of Working Fluid and the Heat Transfer Characteristics in Revolving Heat Pipe Heat Exchanger)

  • 이기우;박기호;전원표
    • 에너지공학
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    • 제10권3호
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    • pp.214-222
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    • 2001
  • 회전형 히트파이프는 다수의 히트파이프 요소를 원통형으로 열교환기를 구성하고 회전시키므로서 열전달 효과를 향상시키고 배가스에 포함되어 있는 분진대책을 용이하도록 하여 오염폐가스에 대해서도 연속적으로 운전을 가능하게 하기 위한 것이다. 이러한 회전형 히트파이프 요소는 작동유체의 귀환을 원심력을 이용하여야 하므로 중심회전측과 2$^{\circ}$내지 5$^{\circ}$경사각으로 조립하여 회전반경을 갖고 회전하는 것이다. 본 연구에서는 회전형 히트 파이프식 열교환기의 구성요소인 히트파이프요소에 대해서 회전반경, 경사각 및 회전속도에 따라 작동유체의 귀환력에 대한 이론해석을 수행하였다. 한열당 20개씩 총 60개의 히트파이프요소가 3열로 배열된 열교환기를 제작하여 성능실험을 수행하였고, 비회전형 히트파이프열교환기와 성능을 비교하여 16%정도의 성능향상이 있음을 알았다.

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스마트워크센터 환경에서 협업을 위한 좌석 추천 시스템 개발 (Development of Seat Recommendation System for the Collaboration in Smart Work Center)

  • 배성문;한관희;최상현;박주현
    • 대한산업공학회지
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    • 제40권1호
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    • pp.128-134
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    • 2014
  • With the development of Information Communication Technology and a way of solving problems such as productivity improvement, advanced working attitude, greenhouse gas reduction, low birth rate, aged problem, etc., the need of smart work is increasing. Getting out of legacy working types that are limited in time and space, the flexible seat system at a smart work center that supports the smart working environment is proposed. However, the seat choice based on employee's emotional judgement may cause the decline of forming cooperative space and mutual communication because of the scattered seat arrangement between employees. This paper proposed a seat recommendation method for the mutual cooperation at a smart work center. The method is based on a work similarity of employees. A prototype system also implemented to show the feasibility.

왕복동식 압축기의 밸브거동과 압력맥동에 대한 연구 (Valve Motions and Gas Pulsations of a Reciprocating Compressor)

  • 이성욱;홍성철;주재만;박철희
    • 소음진동
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    • 제9권4호
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    • pp.754-760
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    • 1999
  • The valve motions of a reciprocating compressor generate the pressure fluctuation at the plenum which is a main source of noise and vibration of a compressor unit. But a cycle of a compressor process consists of complicated phenomena interacting in a short period of time. A mathematical model is developed by simplifying and idealizing the complicated phenomena to simulate the compressor process. The governing equations about the pressure and working fluid flow are developed from the unsteady Bernoulli equation. The pressure fluctuations at the plenums are derived from the Helmholz's resonator model. The valves are modeled as one degree of freedom spring-mass-damper system. This model is verified by the experimental results.

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증착조건에 따른 undoped ZnO 박막의 특성 변화 (Property variations of undoped ZnO thin films with deposition conditions)

  • 남형진;이규항;조남인
    • 반도체디스플레이기술학회지
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    • 제7권3호
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    • pp.51-54
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    • 2008
  • In this study, we investigated variations in undoped ZnO thin film properties with working pressure, $O_2$/Ar ratio, and annealing ambient. Higher vacuum pressure during deposition was observed to bring about slower growth rate resulting in samples with better crystallinity as well as hole generation efficiency through formation of shallower oxygen interstitial. Given that $O_2$/Ar ratio is greater than unity, O provided from the ambient to ZnO during annealing was found to preferably situate at interstitial sites. When He was used for the second annealing, significant changes were not observed. On the other hand, O ambient caused increased density of oxygen interstitial, thereby making the film more intrinsic-like high resistivity ZnO.

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소성가공이 멤브레인 피로 수명에 미치는 영향 (The Effect of Plastic Working on the Membrane Fatigue Life)

  • 윤인수;김영균;김정규
    • 한국가스학회:학술대회논문집
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    • 한국가스학회 2005년도 추계학술발표회 논문집
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    • pp.193-198
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    • 2005
  • An investigation was made on the fatigue characteristics of type 304 stainless steel membrane manufactured by plastic working. To investigate the effect of plastic deformation, tests were performed with 5 types of specimens having different amount of plastic deformation. Fatigue tests were executed under both room and LNG temperatures ($-162^{\circ}C$). All the test results were compared with the fatigue data provided by RPIS(Recommended Practice for Inground LNG Storage Tank). On the basis of these results, it was confirmed that RPIS's design fatigue curve could be applied to evaluate fatigue lift of KOGAS membrane manufactured by pressing.

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Filter 조립 자동화 시스템 설계에 관한 연구 (A Study on the Design of Filter Assembly Automation System)

  • 김홍건
    • 한국공작기계학회논문집
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    • 제17권6호
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    • pp.111-117
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    • 2008
  • An automation process of filter unit is presented for the application of the assembling procedure and dry furnace work. By that automation procedure, it is expected to enhance working environment such as reducing laboring load, harmful gas, and burning scald. Furthermore, this automation process also minimizes via standardization of manufacturing process so that it may increase productivity and reliability. An automation process of filter unit is presented for the application of the assembling procedure and dry furnace work. Filter automation process also gives a good quality and productivity by simplifying to only one line from the complicated process such as filter cutting$\rightarrow$ adhering$\rightarrow$fabricating in a very small space. It is found that a new conceptual design of dry furnace shows the better quality like uniform heat distribution compared to the conventional design. It is also found that the present design gives a better working environment by adding cooling system.

측온저항체 온도센서용 백금 박막의 증착과 그 특성 (The Deposition of Platinum Thin Films for RTD and its Characteristics)

  • 정귀상;노상수
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 1996년도 춘계학술대회 논문집
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    • pp.224-227
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    • 1996
  • Platinum thin films were deposited on Si-wafer by DC magnetron sputtering for RTD (Resistance Thermometer Devices). We investigated the physical and electrical characteristics of these films under various conditions, the input power, working vacuum, temperature of substrate and also after annealing these films. The deposition rate was increased with increasing the input power but decreased with increasing Ar gas pressure. The resistivity were decreased wish increasing the temperature of substrate and the annealing time at 1000$^{\circ}C$. At substrate temperature 300$^{\circ}C$, input power 7(w/$\textrm{cm}^2$), working vacuum 5mtorr and annealing conditions 1000$^{\circ}C$, 240 min we obtained 10.65${\mu}$$.$cm, resistivity of Pt thin film closed to the bulk value.

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측온저항체 온도센서용 백금박막의 형성에 관한 연구 (The study on formation of platinum thin films for RTD temperature sensor)

  • 정귀상;노상수
    • E2M - 전기 전자와 첨단 소재
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    • 제9권9호
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    • pp.911-917
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    • 1996
  • Platinum thin films were deposited on Si-wafer by DC rnagnetron sputtering for RTD (resistance thermometer devices). We investigated the physical and electrical characteristics of these films under various conditions, the input power, working vacuum, temperature of substrate and also after annealing these films. The deposition rate was increased with increasing the input power but decreased with increasing Ar gas pressure. The resistivity and sheet resistivity were decreased with increasing the temperature of substrate and the annealing time at 1000.deg. C. At substrate temperature of >$300^{\circ}C$, input power of 7 w/cm$^{2}$, working vacuum of 5 mtorr and annealing conditions of 1000.deg. C and 240 min, we obtained 10.65.mu..ohm..cm, resistivity of Pt thin films and 3800-3900 ppm/.deg. C, TCR(temperature coefficient of resistance). These values are close to the bulk value. These results indicate that the Pt thin films deposited by DC magnetron sputtering have potentiality for the development of Pt RTD temperature sensor.

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