• BMB Reports
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• v.41 no.2
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• pp.153-157
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• 2008

The objective of the present study was to identify mitochondrial components associated with the damage caused by iron to the rat heart. Decreased cell viability was assessed by increased presence of lactate dehydrogenase (LDH) in serum. To assess the functional integrity of mitochondria, Reactive Oxygen Species (ROS), the Respiratory Control Ratio (RCR), ATP and chelatable iron content were measured in the heart. Chelatable iron increased 15-fold in the mitochondria and ROS increased by 59%. Deterioration of mitochondrial function in the presence of iron was demonstrated by low RCR (46% decrease) and low ATP content (96% decrease). Using two dimensional gel electrophoresis (2DE), we identified alterations in 21 mitochondrial proteins triggered by iron overload. Significantly, expression of the $\alpha$, $\beta$, and d subunits of $F_1F_o$ ATP synthase increased along with the loss of ATP. This suggests that the $F_1F_o$ ATP synthase participates in iron metabolism.

• Journal of Korean Public Health Nursing
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• v.21 no.2
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• pp.193-205
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• 2007

Purpose: To evaluate the current status of utilization and implementation of health promotion programs for Korean middle-aged women in public health centers. Methods: Three-phase stratified sampling was done to select 1304 middle-aged women (aged 40-64 years) from all regions of Korea. The data were collected by face-to-face interviews using a structured questionnaire for individual responses and mailed surveys to 126 public health centers. Descriptive statistics and $x^2$-test were done for data analysis. Results: Only 12 of the 126 public health centers (9.9%) implemented health promotion programs for middle-aged women, with the lack of manpower being cited as the main reason for the absence of programs. From individual responses, 11.3% had participated in health promotion programs offered by public health centers. The main reasons for not participating were inconvenient times and lack of information. Significant differences were found in the frequency of participation in programs, exercise programs and diabetes management according to the size of region. The majority of the respondents cited the need for medical services, followed by programs focused on stroke prevention and leisure time management. The responses on the willingness to participate followed a similar pattern. Conclusion: There are gaps between the utilization of health promotion programs by middle-aged women and what is offered by public health centers. The results of this study support the need to develop more health promotion programs focusing specifically on the needs of middle-aged women.

• Journal of Engineering Education Research
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• v.17 no.6
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• pp.46-52
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• 2014

In order to aware the situation and factors of women students' dropout from engineering college, the factor analysis for women students in P university was performed. The results showed responses that social cultural effects is more significant ones than social effect alone, and the effects of negative gender cognition in industrial circle and college to the women employees and coeds are more significant than effects of regional or positional ones. Also showed responses that the physical difference from man students, the ability for handling machine and tools, her parents' moral support, the gender cognitive engineering education and the boosting for job recruiting are more significants effects than the scholastic ability or the ageism. This may lay the foundation to make a curriculum for women included engineering education that emphasize the gender cognitive approach and the circumstances.

• Proceedings of the Zoological Society Korea Conference
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• 2000.10a
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• pp.227-227
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• 2000

No Abstract, See Full Text

• Women's Health Nursing
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• v.23 no.1
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• pp.11-20
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• 2017

Purpose: This paper presented a descriptive study which aimed to identify the relationship among menstrual attitude, premenstrual distress and premenstrual coping in Korean college women and to propose fundamental data for the development of guidelines for effective management of premenstrual distress. Methods: The data were collected from 111 college women and analyzed using descriptive statistics, t-tests, ANOVA and Pearson's correlation coefficients. Results: The mean score of premenstrual coping was $3.25{\pm}0.60$ out of 5 points. The 'Awareness and Acceptance of Premenstrual Change' score was highest and the 'Avoiding Harm' score was lowest. Menstrual attitude was significantly related to premenstrual distress (r=.37 p<.001) and the awareness and acceptance style of premenstrual coping (r=-.21. p=.021). And premenstrual distress was significantly related to the self-care coping style of premenstrual coping (r=.30, p=.001), the adjusting energy coping style of premenstrual coping (r=.45, p<.001) and the avoiding harm coping style of premenstrual coping (r=.48, p<.001). Conclusion: Results of this study support that positive attitude about menstruation is necessary for the effective management of premenstrual distress. Also, premenstrual coping programs that consider the level of premenstrual distress will be needed for college women.

• Women's Health Nursing
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• v.2 no.2
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• pp.216-229
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• 1996

Pregnancy and delivery are the God's blessing as well as the right of all married women. But, these are agonizing events for the infertile women. Therefore, supportive nursing care for the infertile women is crucial in the process of diagnosis and treatment of infertility. The introduction of In Vitro Fertilization is a solution for infertility. But we take it serious that such socio-cultural factors as patriarchism, sex role, and motherhood are negatively influencing infertility women's experiences. Thus, nurses who take care of the infertile women need to have feministic perspectives as well as medical information, and expertise so that they could reach a comprehensive understanding on infertile women's experiences.

• YAKHAK HOEJI
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• v.60 no.3
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• pp.101-106
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• 2016

Allylthiopyridazine derivatives were synthesized and evaluated for anti-proliferative activities in the previous study. In this study, selected two allylthiopyridazine derivatives (compound I, 3-heptylamino-6-allylthiopyridazine and compound II, 3-dipentylamino-6-allylthiopyridazine) were assessed for cytotoxicity and chronic proliferation in human colon carcinoma RKO cells. Two derivatives dose-dependently inhibited cell viability and proliferation. To elucidate the anticancer mechanism of two derivatives, we investigated the expression level of apoptosis-related proteins in RKO cells. Compound I induced the activation of JNK and expression of p53 and p21. On the other hand, compound II showed no change of p53 level. Interestingly, compound II inhibited the nuclear translocation of NF-${\kappa}B$. This result suggested that compound II suppressed cell proliferation. These different mechanisms of these compounds might have occurred through different steric conformation.

• Women's Health Nursing
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• v.14 no.2
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• pp.143-149
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• 2008

Purpose: This study was done to examine the relationship between self-reported attachment style, trait anger and anger expression in adolescent women. Method: Five hundred and eighty adolescent women were recruited from March to May, 2006. The instruments were Spielberger's state-trait anger expression inventory-Korean version (Chon, Han, Lee, & Spilelberger, 1997), and Batholomew & Holowitz's attachment style Questionnaire (1991). Data was analyzed by descriptive statistics, and ANOVA using the pc-SPSS (version 10.0) program. Result: The mean score of trait anger and anger-in were higher in adolescent women with an insecure attachment style compared to women with a secure attachment style. Conclusion: This finding suggests that family environment factors such as attachment styles are related to trait anger and anger expression in adolescent women. There is a need to further clarify the relationship of attachment style, trait anger and anger expression in adolescent men.

• Journal of East-West Nursing Research
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• v.3 no.1
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• pp.68-82
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• 1998

This study attempted to develop fundamental data of nursing intervention for Women's health improvement through literature review related to women's health. Women's health problems are focused in nursing because the quality of women's health influences on public health directly and indirectly. Especially women experience more stressors and mental disorders than men. This paper reviewed rationale of mental problems to understand Women's mental problems through various research paper analysis. As a result, it was found that women's mental problems as well as the health were affected by various factors and were connected with social, cultural elements closely. This result means that women are affected by social, economical, psychological states from gender unequality in this society. So to solve the women's mental problems, women have to be considered as human beings, women, mothers with multiple roles. And like Hwabyung, one of the women's mental problems related to Korean traditional culture, nursing needs to be done to solve the problem through cultural approach. To do this, nursing has to research negative effect as well as positive effect on women's mental health by modern culture which includes "Han" and traditional family culture. The multidisplinary, interdisplinary communication is important to develop nursing intervention and nursing must build a pertinent Korean women's mental health research system to improve a sociopolitical environment.

• Women's Health Nursing
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• v.28 no.1
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• pp.74-75
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• 2022