• Journal of Korean society of Dental Hygiene
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• v.16 no.5
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• pp.717-723
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• 2016

Objectives: The purpose of the study is to investigate the relationship between safety and health activities of clinical dental hygienists. Methods: A self-reported questionnaire was completed by 208 dental hygienists in Seoul, Gyeonggido, and Incheon from May 9 to June 30, 2016. The study was approved by institutional review board (IRB). The questionnaire consisted of general characteristics of the subjects (9 items) and safety activities (15 items), and health activities (17 items) by Likert 5 point scale. Except two incomplete answers, data were analyzed using SPSS 22.0 program. Results: The mean of safety activities and health activities was 3.04 and 3.55, respectively. A significant difference was shown in staff safety, facility safety, environmental safety, infection control, and dental technique control (p<0.001). Conclusions: A significant association was shown in safety and health activities of clinical dental hygienists. It is necessary to promote the safety and health activities for the clinical dental hygienists.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.31 no.4
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• pp.396-416
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• 2021

Objectives: This study was conducted to analyze the trends of government R&D (R&D) projects related to laboratory safety over the past 20 years. Methods: We collected publications from various databases(DBs) with words such as laboratory(ies), lab(s), researcher(s), laboratory worker(s), safety, environment, hazard(s), risk(s), and so on. Selected publications were analyzed by the research funds and the number of projects according to the investment subject and research characteristics. Results: About 93% of the total R&D budget went to government policy projects, not scientific research. Second, from the perspective of 'safety management activities', most of the research is related to management and inspection at the organizational level. Issues that need to be discussed at the national level like policy governance are not included. Third, focusing on the 'safety management cycle', there were few studies related to 'prediction' or 'post-response'. Fourth, when an analysis framework combining the perspectives of 'safety management activities' and 'safety management cycle' is applied, most of the budget is spent on infrastructure such as digital management systems, whereas basic knowledge for prevention and production of evidence was very few. Conclusions: In order to prevent policy planning without policy evaluation, implementation without strategy, and evaluation without evidence, it is necessary to expand investment in empirical research on risks, research on the effectiveness of current application methods, and research on theory development. The government budget for laboratory safety-related projects should be managed separately from the R&D budget for scientific research. Although less than 5% of the budget allocated to scientific research is the total budget, an optical illusion occurs because both the project budget and the scientific research budget are counted as R&D budgets.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.11
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• pp.4567-4570
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• 2014

Background: This systemic analysis was conducted to evaluate the efficacy and safety of pemetrexed based chemotherapy in treating patients with metastatic breast cancer as first or second line chemotherapy. Methods: Clinical studies evaluating the efficacy and safety of pemetrexed based regimens on response and safety for patients with breast cancer were identified using a predefined search strategy. Pooled response rate (RR) of treatment were calculated. Results: In first line pemetrexed based regimens, 10 clinical studies which including 513 patients with advanced breast cancer were considered eligible for inclusion. For second line pemetrexed based chemotherapy, 5 clinical studies which including 281 patients with advanced breast cancer were considered eligible. Systemic analysis suggested that, in all patients, pooled RR was 32.6% (167/513) in pemetrexed based first line regimens, and 13.9 % (39/281) in pemetrexed based second line regimens. Major adverse effects were neutropenia, leukopenia, fatigue, and anemia in pemetrexed based first line treatment; and lymphopenia, neutropenia, leukopenia, as well as anemia in second line chemotherapy. One treatment related death occurred with pemetrexed based second line treatment. Conclusion: This systemic analysis suggests that pemetrexed based first line regimens are associated with a reasonable response rate and acceptable toxicity, however with low response rate for treating patients with metastatic breast cancer when is used in the second line.

• Journal of East-West Nursing Research
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• v.4 no.1
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• pp.34-43
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• 1999

This study reviewed about Health Management of Women's with Menstrual Disorder and the differences in opinions between the Eastern- Western Nursing Sciences. The purpose of this study was to find out a possible integration of the Eastern-Western Nursing Sciences for Health Management of Women's with Menstrual Disorder and to suggest a distinct frame of Korean Nursing Intervention Method. In the last decade, the women's movement has succeeded in changing in inappropriate and poor treatment. The health consumer movement has also achieved many gains in improving the quality of health care. Yet the medical care offered women during their life stages is still characterized by a lack of effectiveness, safety, and consideration. Today, Although there are differences between Oriental and Western Medicine in approaches to clients, the Eastern-Western Nursing Sciences in approach to clients can be hoped that contribution will be made to the development of nursing intervention which is suitable to Korean context.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.12
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• pp.374-382
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• 2018

The aim of this study was to identify how information media about patient safety incidents influences nursing students' knowledge, perception, and confidence in performance toward patient safety. A total of 337 nursing students agreed to participate in this study. Data were collected from the participants between June 4 and June 12, 2018. Data were analyzed using descriptive statistics, t-test, one-way ANOVA, and Pearson's correlation coefficient with SPSS 21.0. Participants' scores for knowledge, perception, and performance confidence toward patient safety were $6.43{\pm}1.92$, $41.02{\pm}4.35$, and $39.61{\pm}5.89$, respectively. Patient safety knowledge was significantly different according to age, grade, and patient safety education experience. Patient safety perception was significantly different according to satisfaction with the major, patient safety performance confidence showed statistically significant differences according to grade, patient safety education experience, and major satisfaction. Information media exposure to patient safety incidents on TV and knowledge (r=.32, p<.000) and performance confidence (r=.21, p<.000) toward patient safety had positive correlations. Information media exposure to patient safety incidents on the internet and knowledge (r=.34, p<.000), perception (r=.12, p=.028), and performance confidence (r=.24, p<.000) toward patient safety also had positive correlations. This study provides basic data for nursing education and program development for patient safety management.

• Proceedings of the Korean Society of Plant Pathology Conference
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• 2003.10a
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• pp.146.1-146
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• 2003

Transgenic Nicotiana benthmiana plants harboring and expressing coat protein (CP) gene of Zucchini green mottle mosaic virus (ZGMMV) were generated for both virus-resistant screening and complementation analysis of related viruses and environmental safety assessment (SA) of living modified organism (LMO) purposes. Transformation of leaf disc of N. benthamiana was performed using Agrobacterium-mediated method and the pZGCPPGA748 containing the ZGMMV CP and NPTII genes. Two kinds of transgenic homozygous groups, virus-resistant and -susceptible lines, were obtained by screening of challenging homologous virus for T1 generations. Complementation of CP-deficient related virus was analyzed using the susceptible line of ZGMMV. These two pathologically different lines can be useful for host-virus interactions and LMO environmental SA.

• Safe Food
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• v.7 no.1
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• pp.26-31
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• 2012

• Safe Food
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• v.7 no.1
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• pp.15-19
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• 2012

• Safe Food
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• v.7 no.1
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• pp.20-25
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• 2012

• Safe Food
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• v.6 no.3
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• pp.42-63
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• 2011