• (The)Korea Educational Review
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• v.23 no.4
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• pp.53-77
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• 2017

This paper suggests that the meaning and the direction of character education should be understood and approached from a point of view which human formation is regarded as the essence of education. The best way of approach to the character education with this point of view could start from the teachers' character, because teachers are key actors for character formation of students. This study therefore places strong emphasis on the importance of teachers' character and suggesting liberal education, as a key solution, its aim is raising and developing the whole human being. The purpose of this study is to explore the possibility of liberal teacher education. With this purpose of study, the author argues the moral dimension of teaching and the importance of the teachers' role as a character builder in ch.II. In ch.III, the present state of teachers' character education is examined and is argued the necessity of liberal perspective for teacher education to stress the character formation of teachers. The liberal teacher education means that the teacher education is integrated into the quality of liberal education which emphasizes the whole human formation, transformation of personality and critical reflection for human formation. The ch. IV contains exploration of the possibility of liberal teacher education by discussing the compatibility between liberal education and vocational education. Furthermore, it covers how teacher education can reflect the quality of liberal education on the aim of teaching, contents and methods of teacher education concretely.

• Journal of Ginseng Research
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• v.35 no.4
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• pp.442-448
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• 2011

We previously reported that in vitro anti-platelet activity of tissue-cultured mountain ginseng (TCMG) ethanol extracts show improved efficacy when compared with commercial ginseng products such as Korean red ginseng and Panax ginseng. However, information on the anti-platelet activity of the ethyl acetate fraction from TCMG adventitious roots is limited. Therefore, in this study, we further investigated the effects of an ethyl acetate extract of TCMG (EA-TCMG) adventitious roots on in vitro antiplatelet activity in whole human blood and its effect on peripheral blood flow in mice. We found that EA-TCMG inhibited platelet aggregation with $IC_{50}$ values of 271, 180, and 147 ${\mu}g$/mL induced by collagen, adenosine-5'-diphosphate, and arachidonic acid, respectively. Among the three agonists used, thromboxane $A_2$ formation induced by arachidonic acid was markedly suppressed. Furthermore, EA-TCMG improved the peripheral circulatory disturbance by improving vascular blood flow. In conclusion, these results suggest that ethyl acetate extracts from TCMG adventitious roots might inhibit vascular platelet aggregation and thrombus formation.

• Restorative Dentistry and Endodontics
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• v.47 no.4
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• pp.42.1-42.11
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• 2022

Objective: This study investigated the effects of various concentrations of sodium hypochlorite (NaOCl) on human whole-blood clotting kinetics, the structure of the blood clots formed, and transforming growth factor (TGF)-β1 release. Materials and Methods: Human whole blood was collected from 5 healthy volunteers and divided into 4 groups: CG (control, 0.5 mL of blood), BN_0.5 (0.5 mL of blood with 0.5 mL of 0.5% NaOCl), BN₃ (0.5 mL of blood with 0.5 mL of 3% NaOCl), and BN_5.25 (0.5 mL of blood with 0.5 mL of 5.25% NaOCl). The effects of NaOCl on clotting kinetics, structure of fibrin and cells, and release of TGF-β1 were assessed using thromboelastography (TEG), scanning electron microscopy (SEM), and enzyme-linked immunosobent assay, respectively. Statistical analysis was conducted using the Kruskal Wallis and Mann-Whitney U tests, followed by the post hoc Dunn test. A p value < 0.05 indicated statistical significance. Results: The blood samples in BN_0.5 and BN₃ did not clot, whereas the TEG of BN_5.25 showed altered clot formation. Samples from the CG and BN₃ groups could only be processed with SEM, which showed that the latter lacked fibrin formation and branching of fibers, as well as clumping of red blood cells with surface roughening and distortion. TGF-β1 release was significantly highest in BN₃ when all groups were compared to CG (p < 0.05). Conclusions: Each concentration of NaOCl affected the release of TGF-β1 from blood clots and altered the clotting mechanism of blood by affecting clotting kinetics and cell structure.

• Journal of the Korean Society of Costume
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• v.39
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• pp.21-37
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• 1998

This study researchs forms of Egyptian religious dress for studying formation-process of religious dress and its ornament. The study goes abreast literature and the very spot's materials also divides god's dress, priest's. Ancient an egytian worshiped mainly animals, step by step animal's humanization. So gods were expressed animal's face and human's body. Egypt god's costume is 1st, to take off upper hament and wear loin cloth on trousers 2nd only to wear short sheath skirt. 3rd to wear shout sheath skirt and to skirt and to wear loin cloth on there 4th to cover whole body and to open hand like mummy. Egype goddess' costume is largely to wear long sheath skirt up to the ankle and we can see selkit goddess's figure that wearing kalasiris after new dynesty. Priest had been a bald head and worn loin cloth and surrounded leopard's skin on there, but after the period of empire, worn a wig and worn less stoically. Also god had hung the lion's tail at symbol of the dignity and priest had put on sandals for a ceremony.

• Journal of Food Hygiene and Safety
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• v.11 no.2
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• pp.77-82
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• 1996

Green tea catechins(GTC) were studied for its inhibitory effect on human platelet aggregation in vitro, for its antithrombotic effect in mice in viro, and bleeding and clotting time in rats. The catechins were isolated and purified from green tea, which were composed of (-)-epigallocatechin gallate, (-)-epigallocatechin, (-)epicatechin gallate and (-)-epicatechin, GTC produced a potent inhibition of human platelet aggregation in a dose-dependent manner against the stimulants such as ADP, collagen, epinephrine and ristocetin n vitro. GTC also prevented death due to the formation of pulmonary thrombosis by platelet aggregates in mice in a dose-de-pendent manner in viro. GTC increased the bleeding time, whole blood clotting time and plasma clotting time in rats, too. These results suggest that GTC is a promising antithrombotic agent.

• Preventive Nutrition and Food Science
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• v.15 no.4
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• pp.255-261
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• 2010

Ischemic stroke, a major cause of death and disability worldwide, is caused by occlusion of cerebral arteries that, coupled with or without reperfusion, results in prolonged ischemia (hypoxia and hypoglycemia) and, ultimately, brain damage. In this study, we examined whether methanol extract of the whole plant of Cassia mimosoides var. nomame Makino that grows naturally in Korea, as well as Japan and China, and some of its fractions obtained by partitioning with organic solvents could protect human hepatocellular carcinoma cells (HepG2) under hypoxic condition by inhibiting apoptosis. We also investigated if these extracts could attenuate brain damage in a rat model of 2 hr of ischemia, generated by middle cerebral artery occlusion, and 22 hr of reperfusion. The whole extract ($100{\mu}g$/mL) maintained the cell number at more than half of that initially plated, even after 24 hr of cell culture under hypoxic condition (3% $O_2$). In the absence of the whole extract, almost all of the cells were dead by this time point. This improvement of cell viability came from a delay of apoptosis, which was confirmed by observing the timing of the formation of a DNA ladder when assessed by gel electrophoresis. Of fractions soluble in hexane, ethyl acetate (EA), butanol and water, EA extracts were selected for the animal experiments, as they improved cell viability at the lowest concentration ($10{\mu}g$/mL). The whole extract (200 mg/kg) and EA extract (10 and 20 mg/kg) significantly reduced infarct size, a measure of brain damage, by 34.7, 33.8 and 45.2.0%, respectively, when assessed by 2,3,5-triphenyl tetrazolium chloride staining. The results suggest that intake of Cassia mimosoides var. nomame Makino might be beneficial for preventing ischemic stroke through inhibition of brain cell apoptosis.

• Journal of the Korean Society of Costume
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• v.30
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• pp.69-84
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• 1996

The main current of ancient Korean thought is based on Yuk(易) : which solves the principle of creation of universe letter(文字) which is the principle of geometry and three elements thought of circle square . It's related to the creation principle of the universe and regarded as a sign that demons-trates shows the way to read the mathematical principle. The original form of Korean clothes(Han-Bock, 韓服) is represents the structure of hu-man body which reflects a small universe. So a good structure and meaning of the human body is well read in the formation of Korean clothes(Han-Bock, 韓服) and that is a good symbolization of the clothes(Han-Bock, 韓服) as the space of small universe. The good formation of Korean clothes(Han-Bock, 韓服) could be shown by cutting out straight bending twisting and turning each straitly cutting piece is applied to its trans-tormation. Geametical formation with obvious sym-metric dividing of front-back left-right and top-bottom is well shown in Korean clothes by twisting Yuk(易) or m bius strips. So we can find out whole formation by representing only either 'front and back' or 'left and right' and also sa-pok(사폭) of man's trousers seop(섶) of jeo-go-ri(short jacket 저고리) kyut-ma-gi(곁마기) of Sam-hwai-jang jeo-go-ri (삼회장 저고리), mu(무) of jig-ryung(straight collar and long and wide sleeved robe, 直領) trouser wide and ga-rae-ba-dae(가래바대) of dan-cok-kok(woman's under trousers). The formation line of Korean clothes(Han-Bock, 韓服) is based on theprinciple of unlimited m bius strips by twisting of turning direction from universal principle and original basic form is not changd even by turning in-side out. Unity of the whole and part in Korean clothes(Han-Bock, 韓服) could be found in nonorientable thought(非始原思想) which represents the unity and dependence kil(길) of jeo-go-ri(short jacket, 저고리) and po(long and wide sleeved robe, 袍). Selva-gewise(식서방향) of sleeves and seam of out-side of kil(길) and outside of seop(섶) are directed to outside of seop(섶) inside of seop(섶) is to kil and direction of inseam of kheut-dong(끝동) and kyut-ma-gi(곁마기) is directed to sleeves. Korean clothes(Han-Bock, 韓服) is usually made by cutting fabric for several parts and sewing them and the way to make Korean clothes is deeply related to the theory of chon-pu-kyung jong-il and il-seok -sam-geuk. As the development of men's consciousness is pro-gressed from total separation to separation and superseparation. Sewing process of korean clothes(Han-Bock, 韓服) can be make single dimension to double or triple dimension of korean clothes(Han-Bock, 韓服) silhoutte bacause it can be include principle of topology as noneuclity.

• Journal of the Korean Society of Tobacco Science
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• v.20 no.2
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• pp.218-224
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• 1998

Long-term exposure of cigarette smoke or air pollutants to human can induce damages in the airway mucociliary function and can be closely related to the irritation and sputum formation in the respiratory system. This study was undertaken to investigate whether rat trachea can be used as a tool for evaluating the cigarette smoke quality. It was identified that, through the examination with inverted microscope, ciliary beating in 1 mm long cut of nat trachea ring was continued for at least 48 hours in saline solution at $25^{\circ}C$. The ciliostasis time in a KCN solution as a positive control was decreased with increasing the concentration of KCN. There were no significant differences in the ciliostasis time by body weight and individual variation of rats. Ciliotoxicity of whole smoke trapped in saline was not significantly changed by aging for more than 6 hrs. The ciliostasis time was in inverse proportion to the number of sample cigarettes applied. As moisture in the cigarette was increased, ciliostasis time was linearly increased. Therefore, these data indicate that the ciliotoxicity test using rat trachea in vitro can be applied to evaluate the cigarette smoke quality and to search factors for the irritation and sputum formation by cigarette smoke as well as air pollutants.

• Molecules and Cells
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• v.19 no.2
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• pp.167-179
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• 2005

The cells of metazoans respond to DNA damage by either arresting their cell cycle in order to repair the DNA, or by undergoing apoptosis. This response is highly conserved across species, and many of the genes involved in this DNA damage response have been shown to be inactivated in human cancers. This suggests the importance of DNA damage response with regard to the prevention of cancer. The DNA damage checkpoint responses vary greatly depending on the developmental context, cell type, gene expression profile, and the degree and nature of the DNA lesions. More valuable information can be obtained from studies utilizing whole organisms in which the molecular basis of development has been well established, such as Drosophila. Since the discovery of the Drosophila p53 orthologue, various aspects of DNA damage responses have been studied in Drosophila. In this review, I will summarize the current knowledge on the DNA damage checkpoint response in Drosophila. With the ease of genetic, cellular, and cytological approaches, Drosophila will become an increasingly valuable model organism for the study of mechanisms inherent to cancer formation associated with defects in the DNA damage pathway.

• Proceedings of the Korean Institute of Interior Design Conference
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• 2006.05a
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• pp.145-149
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• 2006

China which has 960km of domain area is one of the biggest countries in the world. Also China has a large population of 1,300,000,000 which are 25% of total world population and consist of 56 ethnic groups. In addition, History of China is immemorial and Confucianism of feudalistic and Taoism idea have effect on Chinese for a long time and architecture is influenced by them. Thus a large degree of variety, abundance, and uniqueness can be found in Chinese traditional dwelling. This research will be focusing on Sanapwon, a traditional housing in Beijing, which represents China's original and distinctive dwelling features. By looking at Sanapwon, we can learn the distinguishable characteristics of Chinese residential area and understand the concept of space. By looking closely at the worldly outlook, historical view, originality, and the spatial notion centered around human beings, many types of Sanapwon and its formation process have been examined Likewise indoor plane construction, and basic element of composition of space will help to study the whole of residing space.