• 미생물학회지
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• 제11권4호
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• pp.167-174
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• 1973

This study included two parts of investigation, the microfloral changes during the brewing process with the changes of pH, total acidity, temperature and alcoholic contents, as well as determination of survival times of major enteric pathogens in Takju. 1. Maximum number of Saccharomyces cerevisiae was $4.3{\times}10^7$ per milliliter on the 5th day of fermentation and gradually decreased. Saccharomyces cerevisiae was one of the predominant strains of the fermentation process. The number of Saccharomyces cerevisiae was $4.3{\times}10^6$ per milliliter at the completion of the brewing and human consumption. In a few days after the completion of the brewing. Bacillus subtilis and some species of Staphylococcus spp. began to grow and those organisms were responsible for the spoilage. 2. Maximum pH, during the brewing, was 5.8 on the first day of fermentation and rapidly decreased until 6th day of fermentation at pH 4.3. 3. Maximum alcholic content was 14.5 degree on the 4th day of fermentation, 10.3 degree on the 5th day and this degree was continued during the experimentation. 4. Maximum temperature, during Takju brewing was 34.deg.C on the 3rd day of fermentation and rapidly decreased up to 23.deg.C on the 6th day and this temperature was continued until the brewing process was finished. 5. Maximum total acidity was 0.57 percent on the 4th day of fermentation and gradually decreased by brewing process was completed. 6. Survival time of major enteric pathogenic bacteria in Takju was as follows : Shigella dysenteriae and Escherichia coli were isolated in two hours and 14 hours respectively, but Salmonella typhi, Vibrio parahemolyticus were not isolated even in an hour after the inoculation of those organisms in undiluted Takju. In diluted Takju, Salmonella typhi, Vibrio parahemolyticus were not isolated even in an hour after the inoculation of those organisms in undiluted Takju. In diluted Takju, Salmonella typhi, Shigella dysenteriae, and Escherichia coli were survived for 50-60 hours, but Vibrio cholerae and Vibrio parahemolyticus were not isolated even if treated within one hour.

• Journal of Nutrition and Health
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• 제42권4호
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• pp.338-349
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• 2009

We aimed to evaluate the effect of nutrition education program on nutrition knowledge, dietary behavior, dietary intakes and anthropometric parameters in primary school children. Eighty five 4th grade children (boys = 43, girls = 42) were enrolled in the intervention program for 5 months. The subjects were asked to fill out a questionnaire about nutrition knowledge and dietary behavior two times, at the baseline and after completion of the program. Dietary intake information was collected from participants using a 3-day food record and their anthropometric parameters were measured. Upon completion of the intervention program, both nutrition knowledge and dietary behavior scores were significantly improved in all subjects. Energy intake was increased from 1,571.9 kcal to 1,734.1 kcal with significant improvements in nutrient density for protein, Ca, P, K, vitamin A and niacin. While subjects' height, weight, lean body mass and soft lean mass were significantly increased during the program, significant decreases were observed in the rohrer index, percent body fat, waist-hip ratio and body fat mass. The changes in nutrition knowledge scores were positively correlated with the changes in dietary behavior scores, micronutrient intakes and anthropometric parameters. These results indicate that enhancement of nutrition knowledge through well-planned long-term nutrition education program is effective not only for the improvement of dietary behaviors and dietary intakes but also for the positive changes in anthropometric parameters among primary school children.

• Asian Pacific Journal of Cancer Prevention
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• 제17권8호
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• pp.4031-4035
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• 2016

Background: In the adjuvant treatment of breast cancer, anthracycline and taxane based regimens can be used concomitantly or sequentially. The best order in the sequential regimens has yet to be well established. This study evaluated the feasibility of 4 cycles of adjuvant taxotere ($100mg/m^2$) every 3 weeks followed by 4 cycles of doxorubicin ($60mg/m^2$) and cyclophosphamide ($600mg/m^2$) every 3 weeks. The primary outcome was the safety profile. Secondary outcomes were disease free survival (DFS) and overall survival (OS). Materials and Methods: This non-randomize prospective phase II stud was performed at Jordan University of Science and Technology and its affiliated King Abdulla Teaching Hospital between July 2009 and August 2010. Data collection was closed on May $31^{th}$, 2015 giving a median follow up period of 62 months. The study was approved by the institutional review board and a written informed consent was obtained for each patient. Results: Fifty patients were enrolled. The median age was 53.1 years (range 34-76). One patient (2%) had stage I disease, 17 (34%) stage II, and 32 (64.0%) stage III. Forty-six patients were evaluable for efficacy analysis. The completion rate was 95.7%. No dose modifications were needed. The incidences of grade 3-4 neutropenia and febrile neutropenia were 14 % and 10%. No grade 3-4 non-hematological adverse events were encountered. At a median follow up time of 62 months the OS and the DFS rates were 76.1% and 56.5%. Those for stages I and II combined were 100% and 75%. Conclusions: Taxotere first followed by doxorubicin-cyclophosphamide appears a feasible regimen as evidenced by an acceptable completion rate, a satisfactory safety profile, and an OS and DFS rates comparable to other studies.

• 성인간호학회지
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• 제29권3호
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• pp.313-322
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• 2017

Purpose: The purpose of this study was to identify over time the changes of cancer symptom, depression and quality of life (QOL) among people who had stomach or colorectal cancer. Methods: Of the 74 participants recruited, 67 participated in the study. Participants were asked to complete three instruments at three different time. The instruments were the M. D. Anderson Symptom Inventory-Gastrointestinal Cancer Module, Hospital Anxiety Depression Scale, and the Functional Assessment of Cancer Therapy-General. The questionnaires were administered before chemotherapy, toward the end of chemotherapy, and six months after the completion of adjuvant therapy. Data were analyzed using descriptive statistics and repeated measure ANOVA. Results: At the immediately after chemotherapy point, the most frequent symptom was lack of appetite, followed by fatigue and problem with remembering things. The mean score for depression was 8.27 with a prevalence of 31.3%. The mean score for quality of life was 61.88 out of 135. Repeated measures ANOVA showed a significant increase in cancer symptom (F=23.22, p<.001) and depression (F=35.29, p<.001) after chemotherapy. However, improvement was observed 6 months after the completion of chemotherapy. QOL (F=33.73, p<.001) also showed similar patterns as observed with cancer symptom and depression. Cancer symptom was the strongest predictor of QoL at pre-chemotherapy point. but depression was the strongest predictor at immediately after chemotherapy point. Conclusion: Chemotherapy is highly associated with cancer symptom, depression and QOL in patients with cancer. The nursing intervention is needed to relieve depression as well as cancer symptoms to improve QOL in patients undergoing chemotherapy from baseline to follow-up.

• 터널과지하공간
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• 제9권1호
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• pp.20-26
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• 1999

바쿤 수력발전 프로젝트에서 발전댐의 건설은 가배수로 터널의 완공에 따라 시작되믈 공사기간 측면에서 가배수로 터널의 완공시기는 전체 프로젝트에서 매우 중요한 요소이다. 바쿤 가배수로 터널의 내부단면은 물의 저항을 최대한 줄이기 위하여 원형으로 설계되었으며, 내부직경 12m 인 3개의 터널로 구성되어 있다. 일반적으로 터널 시공과정의 마무리 단계에서 수행되는 터널 라이닝 작업은 굴착 및 지반보강 공정과 더불어 시공비와 공사기간에 많은 영향을 끼치므로 적정한 수준의 라이닝 설계가 요구된다. 바쿤 가배수로 터널에 있어, 라이니으이 두께는현장여건에 따라 다소 차이가 있으나 500~700mm로 타설되었다. 가배수로 터널의 원설계안에 따르면 터널내 전체 라이닝에 필요한 보강콘크리트의 철근량은 5,985 ton 이었으나, 암반의 상태와 여러종류의 하중조건을 고려하여 5종류의 철근 보강 콘크리트 유형으로 구분한 후에 각각의 유형에 따른 상세설계를 통하여 최종적으로 소요 철근량을 2,178 ton으로 감소시킬 수 있었다. 감소된 양은 원설계에서 제시된 양의 절반에 해당되며, 이에 따라 공사기간 및 건설비용을 절감시킬 수 있었다.

• 대한의용생체공학회:의공학회지
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• 제25권1호
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• pp.77-82
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• 2004

다양한 한국인의 표준 뇌를 완성하기 위해 영상 획득의 기준을 마련하고, 획득된 한국인의 뇌 영상 데이터들과 피검자들의 개인 정보들을 저장하고 관리하는 데이터베이스 관리 시스템의 개발이 본 연구의 목적이다. 해부학적 영상 획득을 위해 SNR과 CNR이 우수하고 영상획득시간도 줄일 수 있는 3D MP-RAGE 기법을 선택하였고, 최적의 영상 획득을 손잡이 검사, 상태-특성 불안척도 검사, A 유형 성격 검사, 자기평가 우울척도 검사, 사상체질 검사 간이정신 진단검사, 지능진단 검사, 성격요인 검사를 질문지로 수행한 후 그 결과를 저장하고 관리 할 수 있도록 하였다. 또한 본 시스템은 피검자의 영상 정보 및 개인 정보의 저장, 삽입, 삭제, 검색, 출력 기능뿐만 아니라 Access 권한 기능, ODBC와의 연결 설정도 자동으로 수행되도록 개발하였다. 개발된 시스템은 다양한 한국인의 영상 정보와 개인 정보를 저장, 관리 할 수 있기 때문에 다양한 한국인의 표준뇌를 완성하는데 큰 기여를 할 수 있을 것이다.

• Journal of the Korean Wood Science and Technology
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• 제45권2호
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• pp.147-158
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• 2017

Among the energy consumption in building, the heating energy takes the largest part. Therefore, it is important to minimize the heat energy loss in building for the reduction of overall energy use in construction. The most important points for the minimization of energy loss in building are insulation and airtightness. Especially, in wood houses, airtightness is very important for energy saving as well as increase of durability. However, the researches on airtightness of wood buildings have been started recently and are very deficient especially in Korea. In this study, air leakage properties and airtightness performance were evaluated for light-frame wood houses built in Daejeon and Chungnam area. Total 7 houses were evaluated, among which four houses (Case 1 to Case 4) were in the construction stage before interior finish and the other three houses (Case 5 to Case 7) were after completion of construction work. The tests for airtightness were conducted by pressurization-depressurization method, and the factors included in the measurements includes air leakage rate at 50 Pa (CMH50), air change rate at 50 Pa (ACH50), equivalent leakage area (EqLA) and EqLA per floor area. As a result of this study, key air leakage points in wood houses were found to be the gaps between floor and wall, the holes for wiring and plumbing, the double glasses windows and the entrance doors. The average value of ACH50 for the houses after completion of construction work was $3.5h^{-1}$ that was similar to Europe standard ($3.0h^{-1}$). ACH50 was proportional to EqLA per floor area but inversely proportional to the internal volume, the net floor area and the area of window.

• PNF and Movement
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• 제17권2호
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• pp.275-282
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• 2019

Purpose: This study aimed to investigate the optimal positions of safety grab bars for effective sit-to-stand (STS) movement by comparing the results of the STS movement while using a safety grab bar installed under two different conditions: the height of the grab bar installation was determined by (1) the Building Act and (2) the principle of proprioceptive neuromuscular facilitation (PNF). Methods: A total of 50 undergraduate students participated in this study, and they were required to perform an STS movement twice under each condition. A baropodometric platform for sitting and a Biorescue (RM Ingenierie, France) were used to collect and analyze changes in the center of pressure (COP) on the left and right sides before and after performing the STS movement. The average completion time for the STS movement was also measured for analysis. Moreover, the participants were asked to express their individual subjective preferences regarding the two positions of the grab bars. Results: The COP changes were significantly smaller when performing the STS movement with the grab bar installed at the height determined by the PNF principle than the Building Act (p<0.01), and the difference in the completion time of the STS movement was not statistically significant between the two conditions. Conclusion: The findings of this study suggest that the principle of PNF can be useful for planning therapeutic exercise as well as for proposing the optimal grab bar position for older adults and those with health-related issues when performing the STS movement. In addition, this may serve as a basic rehabilitation technique for maintaining remaining functions and providing functional efficiency.

• 한국가족관계학회지
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• 제21권3호
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• pp.73-93
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• 2016

Objective: The purpose of the present study was to examine how children's transition to adulthood might be related to their parents' marital satisfaction and relationship satisfaction with children. Specifically, we investigated if the numbers of children who (1) graduated from 4-year college, (2) were employed, (3) were married, (4) moved out of parental homes and lived independently, and (5) had at least one child might be associated with better marital satisfaction and higher relationship satisfaction with children among midlife and older parents. We also evaluated if the associations might differ by gender of the children (sons vs. daughters) as well as by their gender and birth order (first-born son, later-born son, first-born daughter, later-born daughter). Method: The analytic sample was drawn from the 2006 Korean Longitudinal Study of Ageing. The sample consisted of 1,905 parents whose children were aged between 25 and 35. For analysis, regression models with robust standard errors were estimated using Stata. Results: Results suggest that sons' (especially first-born sons') transition to adulthood exerted more consistent impacts on parents. More specifically, first-born sons' completion of higher education, marriage, and independent living arrangement were associated with either higher levels of parental marital satisfaction or relationship satisfaction with children. With regard to later-born sons, their completion of college education was linked to higher levels of parental marital satisfaction and relationship satisfaction with children. Conclusion: Korean parents appear to place greater importance on first-born sons' successful transition to adulthood compared to those of other children. Overall, however, transition to adulthood may have limited influence on Korean parents.

• Journal of Dental Anesthesia and Pain Medicine
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• 제21권6호
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• pp.565-574
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• 2021

Background: Trigeminal neuralgia (TN) is a severe form of pain that affects the daily activities of a patient. Transcutaneous electrical nerve stimulation (TENS) therapy is an emerging option for the treatment of acute and chronic pain. The aim of this study was to evaluate the effect of TENS therapy as an adjunct to drug therapy for the treatment of TN. Methods: A total of 52 patients diagnosed with TN according to the International Classification of Headache Disorders (version 3) were included. Each patient was randomized to either the TENS or placebo TENS groups. Intervention was given in continuous mode and 100-Hz frequency for 20 mins biweekly for 6 weeks. Parameters were measured at baseline, TENS completion and 3 months, 6 months, and 1 year of follow up. The parameters observed were mean carbamazepine dose, mean visual analog scale (VAS) score, mean present pain intensity (PPI) score, and functional outcome. Non-parametric analyses, one-way ANOVA and the Kruskal-Wallis test were applied for intragroup comparisons, while the Mann-Whitney U test and independent t-test were used for intergroup comparisons of variables. The chi-square test was applied to analyze categorical data. Results: Compared to the placebo TENS group, the mean dose of carbamazepine in the TENS group was significantly reduced at TENS completion, as well as at 6 months and 1 year follow up. Changes in mean VAS score, mean PPI score, and functional outcome did not show significant differences between the groups (P>0.05). Conclusion: TENS therapy does not lead to any changes in pain levels but it may reduce the mean dose of carbamazepine when used as an adjunct treatment in patients with TN.