• Journal of Korean Neurosurgical Society
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• 제42권2호
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• pp.92-96
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• 2007

Objective : The authors have speculated that metastatic brain lesions from renal cell carcinoma (RCC) show diverse radiological patterns and tumor responses after Gamma knife surgery (GKS), and have hypothesized that these can be predicted from tumor radiological characteristics. The goal of the current study was to identify the radiological characteristics of RCC brain metastases and the predictors of initial radiosurgical response after GKS. Methods : A retrospective analysis was performed on 48 lesions in 18 patients with RCC brain metastasis treated by GKS. The radiological characteristics of these lesions in magnetic resonance images (MRI) were classified into 3 categories according to enhancement patterns in T1-weighted images and signal intensity characteristics in T2-weighted images. Responses to GKS were analyzed according to these categories, and in addition, other potential predictive factors were also evaluated. Results : MRI findings in the three categories were diverse, though numbers of the lesion were comparable. At 2-month MRI follow-ups after GKS, response rate was 54% and the local tumor control rate 83%. T2 signal intensity was found to be the principal predictive factor of response to GKS, namely negative predictive factor. Other variables such as age, sex, tumor volume, dose, duration from initial diagnosis to GKS, and previous systemic therapies failed to show significant relationships with treatment response by multivariate analysis. Conclusion : Careful evaluation of the radiological characteristics of brain metastases from RCC is important prior to GKS because MRI heterogeneity has predictive value in terms of determining initial tumor response.

• 대한영상의학회지
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• 제84권5호
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• pp.1134-1139
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• 2023

메르켈 세포암종은 드문 악성 피부종양으로 주로 두경부에 발생한다. 저자들은 몸통에 발생한 병리학적으로 확진된 메르켈 세포암종의 그레이스케일 및 색 도플러 초음파 소견과 자기공명영상 소견을 보고하고자 한다. 메르켈 세포암종은 초음파상 비균질 에코를 보이고 피부 및 피하층에 수직방향으로 저에코의 '연기기둥' 같은 선형 띠를 가지고 있었으며 내부에 혈류가 약간 증가되어 보였다. 한편 T1강조 자기공명영상에서 저신호강도, T2 및 양자밀도강조영상에서 같은 층에 저신호강도의 선형띠와 함께 고신호강도로 보였으며, 강한 조영증강을 보였다. 메르켈 세포암종의 영상 소견이 비특이적으로 알려져 있지만, 이러한 특징적인 소견들은 이 질환을 조기 진단하는데 도움이 될 수 있을 것이다.

• 한국통신학회논문지
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• 제40권12호
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• pp.2410-2418
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• 2015

In this paper, we consider the femto users and their mutual interference as graph elements, nodes and weighted edges, respectively. The total bandwidth is divided into a number of resource blocks (RBs) and these are assigned to the femto user equipment (FUEs) using a graph coloring algorithm. In addition, resources blocks are assigned to the femto users to avoid inter-cell interference. The proposed scheme is compared with the traditional scheduling schemes in terms of throughput and fairness and performance improvement is achieved by exploiting the graph coloring scheme.

• Journal of Communications and Networks
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• 제18권6호
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• pp.873-883
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• 2016

In this paper, we focus on maximizing weighted sum energy efficiency (EE) for a multi-cell multi-user channel. In order to solve this non-convex problem, we first decompose the original problem into a sequence of parallel subproblems which can optimized separately. For each subproblem, a base station employs dirty paper coding to maximize the EE for users within a cell while regulating interference induced to other cells. Since each subproblem can be transformed to a convex multiple-access channel problem, the proposed method provides a closed-form solution for power allocation. Then, based on the derived optimal covariance matrix for each subproblem, a local optimal solution is obtained to maximize the sum EE. Finally, simulation results show that our algorithm based on non-linear precoding achieves about 20 percent performance gains over the conventional linear precoding method.

• 한국경영과학회지
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• 제25권1호
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• pp.85-92
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• 2000

Channel management is critical in designing a cellular mobile system that offers high capacity and high quality. In this paper, an integrated channel management scheme is proposed, which consists of a dynamic channel allocation scheme and an admission control scheme. The dynamic channel allocation scheme allocates a call request the channel which minimizes the impact on its interfering cell, and consists of two types of channel allocation strategies : nominal channel allocation strategy and non-nominal channel allocation strategy. The admission control scheme named the variable cutoff priority scheme reserves some frequency channels for handoff cells in each cell the number of which varies according to the blocking probability of handoff class in that cell. Computationl tests are performed to evaluate the performance of the proposed scheme in terms of overall blocking probability, defined by the weighted value of the blocking probabilities of new calls and handoff calls. The results show that the proposed scheme yields better performance than other compared schemes.

• 한국컴퓨터정보학회논문지
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• 제7권3호
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• pp.122-127
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• 2002

스케줄링 알고리즘의 일종인 Inna은 매우 간편하며 각 큐에 다른 가중치를 할당하여 여러 큐를 직접 제어한다. 본 논문에서는 WRR 스케줄링 알고리즘을 효율적으로 수행할 수 있는 새로운 BSW 구조를 제안한다. 또한, 새로운 BSW구조에 적합한 셀 스케줄링 알고리즘을 개발한다 제안된 BSW구조와 알고리즘은 VC에 할당된 가중치를 정확히 유지 한 수 있고, 서비스 받을 VC큐가 비어 있을 경우 다른 VC 셀을 서비스하여 평균 셀 지연 및 최대 버퍼 크기를 감소시킨다. 제안된 알고리즘은 WRR 구현에 매우 적합한 구조이다.

• 대한수의학회지
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• 제63권2호
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• pp.9.1-9.5
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• 2023

A 5-year-old Labrador Retriever presented with a subcutaneous mass on the right scapular region with localized calor. On magnetic resonance imaging (MRI), a heterogeneously hypointense mass was seen on T1-weighted images (WI) and hyperintense on T2WI and fat-suppressed T2WI with marginal contrast enhancement on postcontrast T1WI and invasion into the surrounding tissue. Histopathological examination of the mass confirmed subcutaneous mast cell tumor (MCT) infiltrating to the adjacent subcutaneous fat. This is the first report to describe the MRI findings of subcutaneous MCT in veterinary medicine. This study suggests that MRI may help evaluate the extent of invasion of subcutaneous MCT.

• Journal of Korean Neurosurgical Society
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• 제54권6호
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• pp.467-476
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• 2013

Objective : This study aimed to evaluate the hypotheses that administration routes [intra-arterial (IA) vs. intravenous (IV)] affect the early stage migration of transplanted human bone marrow-derived mesenchymal stem cells (hBM-MSCs) in acute brain infarction. Methods : Male Sprague-Dawley rats (n=40) were subjected to photothrombotic infarction. Three days after photothrombotic infarction, rats were randomly allocated to one of four experimental groups [IA group : n=12, IV group : n=12, superparamagnetic iron oxide (SPIO) group : n=8, control group : n=8]. All groups were subdivided into 1, 6, 24, and 48 hours groups according to time point of sacrifice. Magnetic resonance imaging (MRI) consisting of T2 weighted image (T2WI), $T2^*$ weighted image ($T2^*WI$), susceptibility weighted image (SWI), and diffusion weighted image of rat brain were obtained prior to and at 1, 6, 24, and 48 hours post-implantation. After final MRI, rats were sacrificed and grafted cells were analyzed in brain and lung specimen using Prussian blue and immunohistochemical staining. Results : Grafted cells appeared as dark signal intensity regions at the peri-lesional zone. In IA group, dark signals in peri-lesional zone were more prominent compared with IV group. SWI showed largest dark signal followed by $T2^*WI$ and T2WI in both IA and IV groups. On Prussian blue staining, IA administration showed substantially increased migration and a large number of transplanted hBM-MSCs in the target brain than IV administration. The Prussian blue-positive cells were not detected in SPIO and control groups. Conclusion : In a rat photothrombotic model of ischemic stroke, selective IA administration of human mesenchymal stem cells is more effective than IV administration. MRI and histological analyses revealed the time course of cell migration, and the numbers and distribution of hBM-MSCs delivered into the brain.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제26권4호
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• pp.373-382
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• 2000

Temporomandibular disorders arised from joint itself was caused by inflammation or mechanical irritation of the retrodiskal tissues. Histologic changes of the retrodiskal tissues of temporomandibular joint(TMJ) internal derangement, such as inflammatory cell infiltration, hyalinization, myxoid change, fatty change, arterial obliteration, and so on, were reported, but relationships between magnetic resonance imaging(MRI) findings and histologic findings of the retrodiskal tissue were few reported. The purpose of this study was to find histologic changes of the retrodiskal tissues for status of joint and joint effusion in MRI of the temporomandibular joint which had surgical treatment. Materials were surgically treated 52 temporomandibular joints with internal derangement or osteoarthritis in TMJ clinic, Yongdong Severance Hospital. All joints were confirmed by magnetic resonance T1- and T2-weighted imagings bofere surgery. Status of joint was categorized by normal position, disc displacement with reduction, disc displacement without reduction, disc displacement without reduction associated with osteoarthrosis using preoperative MR T1-weighted images. Magnetic resonance evidence of joint effusion was observed in T2-weighted images and classified by its amount; degree 0(not observed), degree 1(small amount), degree 2(moderate amount), degree 3(large amount). Histologic features were observed whether the retrodiskal tissue has inflammatory cell infiltration, myxoid change, hyalinization, chondroid metaplasia and arterial obliteration. The distribution of elastic fibers were also observed. The results were as follows; 1. Inflammatory cell infiltration was not observed in any retrodiskal tissues. 2. MRI findings such as status of joint and evidence of joint effusion did not have significant relationship with myxoid change, hyalinization, chondroid metaplasia, arterial obliteration of the retrodiskal tissues. 3. Hyalinization and chondroid metaplasia were found in 8 joints(15.4%) and 5 joints(9.6%). All of them were found in disc displacement without reduction and disc displacement without reduction associated with osteoarthrosis. 4. Arterial obliteration was observed more frequently in disc displacement without reduction(55.6%) than disc displacement without reduction associated with osteoarthrosis(28.6%). Further studies with proper controls and more materials will be necessary.

• Korean Journal of Radiology
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• 제23권11호
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• pp.1078-1088
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• 2022

Objective: To develop and validate a model using radiomics features from apparent diffusion coefficient (ADC) map to diagnose local tumor recurrence in head and neck squamous cell carcinoma (HNSCC). Materials and Methods: This retrospective study included 285 patients (mean age ± standard deviation, 62 ± 12 years; 220 male, 77.2%), including 215 for training (n = 161) and internal validation (n = 54) and 70 others for external validation, with newly developed contrast-enhancing lesions at the primary cancer site on the surveillance MRI following definitive treatment of HNSCC between January 2014 and October 2019. Of the 215 and 70 patients, 127 and 34, respectively, had local tumor recurrence. Radiomics models using radiomics scores were created separately for T2-weighted imaging (T2WI), contrast-enhanced T1-weighted imaging (CE-T1WI), and ADC maps using non-zero coefficients from the least absolute shrinkage and selection operator in the training set. Receiver operating characteristic (ROC) analysis was used to evaluate the diagnostic performance of each radiomics score and known clinical parameter (age, sex, and clinical stage) in the internal and external validation sets. Results: Five radiomics features from T2WI, six from CE-T1WI, and nine from ADC maps were selected and used to develop the respective radiomics models. The area under ROC curve (AUROC) of ADC radiomics score was 0.76 (95% confidence interval [CI], 0.62-0.89) and 0.77 (95% CI, 0.65-0.88) in the internal and external validation sets, respectively. These were significantly higher than the AUROC values of T2WI (0.53 [95% CI, 0.40-0.67], p = 0.006), CE-T1WI (0.53 [95% CI, 0.40-0.67], p = 0.012), and clinical parameters (0.53 [95% CI, 0.39-0.67], p = 0.021) in the external validation set. Conclusion: The radiomics model using ADC maps exhibited higher diagnostic performance than those of the radiomics models using T2WI or CE-T1WI and clinical parameters in the diagnosis of local tumor recurrence in HNSCC following definitive treatment.