• Analytical Science and Technology
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• v.32 no.6
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• pp.233-242
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• 2019

Substance identification is the first step of the REACH registration. It is essential in terms of Classification, Labelling and Packaging (CLP) regulation and because even trace amounts of impurities or additives can affect the classification. In this study, a scheme for the screening, quantification, and interpretation of trace amounts of hazardous inorganic substances is proposed to detect the presence of more than 0.1% hazardous inorganic substances that have been affecting the hazard classification. An exemplary list of hazardous inorganic substances was created from the substances of very high concern (SVHCs) in REACH. Among 201 SVHCs, there were 67 inorganic SVHCs containing at least one or ~2-3 heavy metals, such as As, Cd, Co, Cr, Pb, Sb, and Sn, in their molecular formula. The inorganic SVHCs are listed in excel format with a search function for these heavy metals so that the hazardous inorganic substances, including each heavy metal and the calculated ratio of its atomic weight to molecular weight of the hazardous inorganic substance containing it, can be searched. The case study was conducted to confirm the validity of the established scheme with zinc oxide (ZnO). In a substance that is made of ZnO, Pb was screened by XRF analysis and measured to be 0.04% (w/w) by ICP-OES analysis. After referring to the list, the presence of Pb was interpreted just as an impurity, but not as an impurity relevant for the classification. Future studies are needed to expand on this exemplary list of hazardous inorganic substances using proper regulatory data sources.

• Journal of the Korean Society of Clothing and Textiles
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• v.31 no.9_10
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• pp.1465-1474
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• 2007

We analyzed the effects of regular Jjimjilbang(Korean sauna) exposure on the heat tolerance in young and old females. Subjects were young(n=7) and old(n=7) females who never had a bath in Jjimjilbang for last year. Jjimjilbang training group took a bath in Jjimjilbang once a week 19 times. Jjimjibang expsure was limited three times per day, Jjimjil were taken free way. To prove the effects of the heat tolerance, Subjects were exposed to hot and humid air$(40.0{\pm}0.5^{\circ}C,\;60{\pm}5%RH)$. In the condition, subjects were taken a foot bathing$(40.0{\pm}0.5^{\circ}C)$ and simulated for 30 min., and rectal temperature, skin temperatures, clothing microclimate, blood pressure, total body weight loss, local sweat and subjective sensation were measured. The results are as follow: Rectal temperature, skin temperatures, clothing microclimate, total body weight and subjective thermal comfort sensation were decreased gradually(p<.001). Local sweat of upper arm was decreased(p<.01). In conclusion. the regular Jjimjilbang exposure has positive effects upon improvement in regulation of body temperature, especially in heat tolerance.

• Fire Science and Engineering
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• v.30 no.2
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• pp.123-132
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• 2016

This study is the result of performing structural analysis in accordance with the new ambulance design of inside space using the new vehicle's bodywork. 3D design works were performed based on international standards and designed ambulance. And then it was tested by a shock of 10G to the ambulance car inside with respect to the vehicle body after that we looked into the consequences. At this time, it was carried out in consideration of its own weight and the weight of components according to the EN regulation. From the result of structural analysis, the internal frame and configured handrail in a variety of pipe did not have a relatively large stress load, but internal panel and cabinets has been interpreted to receive a large stress load at least over 50 MPa. When carried out reinforcement design in accordance with this analysis, the modification of thickness and shape could be necessary. On the basis of these findings, it is also expected that there could be a useful information to produce a more secure vehicle for paramedics and patients using a ambulance inside the vehicle.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.23 no.5
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• pp.551-557
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• 2010

The purpose of this study is to estimate experimentally the flexural behavior, capacity and validity of existing regulation of net tensile strain in lightweight concrete beams and polymer modified lightweight concrete beams. One normal weight concrete beam and four lightweight concrete beams, three polymer modified lightweight concrete beams were constructed as same figure and attempted to evaluate the difference of strength and ductility in specimens of different net tensile strain in extreme tension steel. Test results are indicated in terms of load-deflection behavior and ductility index. As the value of net tensile strain increased, the flexural strength and stiffness of specimen decreased but ductility index increased in both of lightweight concrete beams and polymer modified lightweight concrete beams. It is considered that to achieve similar ductility index of normal weight concrete, net tensile strain in extreme tension steel should exceed 0.005 for lightweight concrete beam and polymer modified lightweight concrete beam.

• The Journal of Pediatrics of Korean Medicine
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• v.21 no.2
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• pp.153-167
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• 2007

Objetives This experimental study is designed to investigate the effects of kwakhyangjungkisangamibang extract on the changes of adipose tissues, serum insulin and leptin levels in rats induced by a high fat diet. The leptin has been proposed to be involved in the role of food intake and energy expenditure. Methods During the 8 weeks of experimental period, male Sprague-Dawley rats were fed on the 2 different diets: the normal diet AIN-76A and high fat(beef tallow) diet ad libitum, of which 40% of the calories intake was fat. 9 rats in the control and high fat diet group were killed for the baseline experiment at 4 weeks of age. The high fat diet group was divided into three groups: control group, experimental group I(high fat diet plus kwakhyangjungkisangamibang extract), and experimental group II(high fat diet plus mahuang). The body weight, hypodermal fat tissue, serum lipid profile, insulin and leptin levels were measured after the administration of the high fat diet and extract. Results 1. The body weight was decreased in experimental group II, but there was not a significance difference compared to the control group. 2. The peritoneal, visceral, and hypodermal adipose tissue was decreased in experimental group I, but there was not a significance difference compared to the control group. 3. The lipid profile was decreased in experimental group I, but not in group II. 4. The insulin concentration was increased in experimental group I and II, but there was not a significance difference compared to the control group. 5. The leptin level was increased significantly in experimental group I(p<0.05) and II(p<0.01) compared to the control group. Conclusion The results of this study indicate that kwakhyangjungkisangamibang has an effect on the regulation of obesity.

• Journal of the Korea Organic Resources Recycling Association
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• v.1 no.1
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• pp.115-125
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• 1993

In Euglena gracilis arginine deiminase was located in the mitochondrial matrix. The highly purified enzyme required $Co^{2+}$ for the enzyme reaction with the $K_m$ value of 0.23 nM, and its optimum pH was 9.7 to 10.3. The molecular weight of the native enzyme protein was 87,000 by gel filtration, and SDS-acrylamide gel electrophoresis showed that the enzyme consisted of two identical subunits with a molecular weight of 48,000. Euglena arginine deiminase was inhibited by sulfhydryl inhibitors, indicating that a sulfhydryl group is involved in the active center of the enzyme. It exhibited negative cooperativity in binding with arginine. $L-{\alpha}-amino-{\beta}-guanidino-propionate$, D-arginine, and L-homoarginine strongly inhibited the enzyme while ${\beta}-guanidinopro-pionate$, ${\gamma}-guanidinobutyrate$, and guanidinosuccinate did not. Considerable inhibition was also observed with citrulline and ornithine. We discuss the effects of the unique properties of the Euglena arginine deiminase on the regulation of arginine metabolism in this protozoon.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.6
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• pp.794-798
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• 2004

An attempt was made to improve the efficiency of growth and lactation performance of dairy heifers subjected to a stair-step growth scheme using rice straw as the sole roughage source. Twenty-four young Holstein heifers were randomly assigned to either control or test group. The control diet met the National Research Council (NRC) requirement, with heifers calving at 24 to 26 mo of age. The test group was individually fed according to a schedule of 3, 2, 4, 2, 5 and 2 mo in which feed intake was alternately 20% below or 25% above the NRC requirements. Heifers on the stair-step growth pattern gained more body weight and consumed less dry matter (10.80 and 11.22%, respectively), resulting an increasing growth efficiency compared with the control. Body condition, first estrus, first conception, services per conception and calving difficulty (data not shown) were not affected. Milk yield of the test group was 8.5% higher than that of the control group. During the early lactation period, the milk yield was significantly higher in the stair-step group than in that of the control group (p<0.05). Milk composition was not affected by compensatory growth induced by the stair-step scheme. Also, weight at calving and calf growth performance was not affected by stair-step growth. The results indicate that using rice straw as a sole roughage source in a stair-step compensatory growth scheme can contribute to the improvement of growth efficiency and early lactation performance.

• Journal of Microbiology and Biotechnology
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• v.30 no.8
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• pp.1132-1141
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• 2020

Inflammatory bowel disease (IBD) is an increasing global burden and a predisposing factor to colorectal cancer. Although a number of treatment options are available, the side effects could be considerable. Studies on fecal microbiota transplantation (FMT) as an IBD intervention protocol require further validation as the underlying mechanisms for its attenuating effects remain unclear. This study aims to demonstrate the ameliorative role of FMT in an ulcerative colitis (UC) model induced by dextran sulfate sodium (DSS) and elucidate its relative mechanisms in a mouse model. It was shown that FMT intervention decreased disease activity index (DAI) levels and increased the body weight, colon weight and colon length of experimental animals. It also alleviated histopathological changes, reduced key cytokine expression and oxidative status in the colon. A down-regulated expression level of genes associated with NF-κB signaling pathway was also observed. The results of 16S rRNA gene sequencing showed that FMT intervention restored the gut microbiota to the pattern of the control group by increasing the relative abundance of Firmicutes and decreasing the abundances of Bacteroidetes and Proteobacteria. The relative abundances of the genera Lactobacillus, Butyricicoccus, Lachnoclostridium, Olsenella and Odoribacter were upregulated but Helicobacter, Bacteroides and Clostridium were reduced after FMT administration. Furthermore, FMT administration elevated the concentrations of SCFAs in the colon. In conclusion, FMT intervention could be suitable for UC control, but further validations via clinical trials are recommended.

• Journal of Korean Public Health Nursing
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• v.12 no.2
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• pp.89-106
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• 1998

The Health Promotion Model by Pender(l987) was used as the conceptual framework for analyzing the health promotion behaviors. The purposes of this study were to describe health promoting life style behaviors in 245 women between the ages of 35 and 59 living in Seoul and other cities and to find their predictive factors. Data were collected from 1st to 23th. June. 1998. The tool used for this study was structured questionnaire with consisted of 8 items on general characteristics. 5 items on health related characteristics. 43 items on health promoting life style. 28 items on menopausal symptoms. 5 items on family support. and 28 items on self-efficacy. The collected data were analyzed using the SAS. yielding descriptive statistics. ANOVA. Pearson's Correlation. stepwise multiple regression. The findings of this study are as follows. 1) The mean score of health promotion behavior(3.25) is not high. The mean scores of this self actualization (3.73). interpersonal support (3.68). and nutrition (3.57). regulation of stress (3.22) in domains are higher than health responsibility (2.90). exercise (2.63). 2) The results of the comparison between the health promotion behaviors and general variables showed a statistically significant difference in education (P=.0061), domestic economy status(P=.0001). perception of health status(P=.0001) but. age. state of menstruation. perception of weight is not significant difference. 3) The correlation between health promoting life style and self-efficacy(P=.0001). family support(P=.0001) is significant. But. there is no correlation between health promoting life style and age. number of family. perception of weight. 4) In the cognitive-perceptual factors. self-efficacy (P=.0001) is very significant predictor (accounted for $39.7\%$) and in the modifying factors. family support(P=.0001) is very significant (accounted for $9.0\%$). It is same to other research results.

• The Journal of Pediatrics of Korean Medicine
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• v.19 no.1
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• pp.53-66
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• 2005

Objectives : Osteoporosis is generally occurred in old age, especially postmenopausal women therefore, it is relatively overlook osteoporosis in children, but the authors have paid attention to bone density in children because maximizing peak bone mass of childhood is advocated as a way to prevent osteoporosis and environmental factor of childhood play role in the regulation of bone density. the present study was performed to measure bone density of children and to assess the influence of age, sex, body size, exercise, weak symptoms on bone density during the period of bone growth. Methods : We have measured bone density of calcaneus bone in 283 children (male 144 female 139, ranged from3 to 18) who visited in growth clinic of Pediatrics, Dongguk University Bundang Oriental Hospital, using quantitative ultra sound densitometry and they were divided into 3 groups by age(3-10, 11-15, 15-18 years). Pearson's correlation was used to assessed the influence of age, body size and Student's t-test was used to detect differences in sex, exercise, weak symptoms between the groups on bone density Results : The bone density correlated with age, height, weight, body mass index in this study. Bone density were significantly higher in males than in female. Digestive weak children's bone density were lower than normal children. Conclusion : Weight-bearing exercise and food rich in nutrition are necessary to increase maximizing peak bone mass in children.