• Title/Summary/Keyword: weight regulation

Search Result 534, Processing Time 0.029 seconds

난황 항체를 이용한 탄수화물의 체내 소화흡수 저해 (Inhibition of carbohydrate digestion using egg yolk antibody)

  • 홍성길;김대원;김정원;이홍석
    • 한국식품조리과학회지
    • /
    • 제18권1호
    • /
    • pp.94-100
    • /
    • 2002
  • The dietary carbohydrates are mainly digested and adsorbed at small intestine. We developed a new food additive as an egg yolk antibody(1gY) against maltase, sucrase and sodium dependent g1ucose cotransporter(SGLT) for the regulation of blood glucose level and weight control. The maltase, sucrase and SGLT were purified from porcine small intestine which is very similar to that of human in physiological characteristics. The purification step contained an ultracentrifugation, ion exchange chromatography and hydrophobic chromatography. The hens were immunized by purified protein and the IgY activities against immunized antigens were determined. This antibody obtained from the immunized hen's egg yolks directly inhibited the activities of maltase and sucrase in vitro. And the IgY delayed and decreased the increment of blood g1ucose level after administration of maltose, sucrose and glucose in rat about 30 to 60%. The results of this study suggest that the IgY inhibiting the carbohydrate digestion could be used as functional food materials for weight control and regulation of blood glucose level in diabetes.

Effect of fructose or sucrose feeding with different levels on oral glucose tolerance test in normal and type 2 diabetic rats

  • Kwon, Sang-Hee;Kim, You-Jin;Kim, Mi-Kyung
    • Nutrition Research and Practice
    • /
    • 제2권4호
    • /
    • pp.252-258
    • /
    • 2008
  • This study was designed to determine whether acute fructose or sucrose administration at different levels (0.05 g/kg, 0.1 g/kg or 0.4 g/kg body weight) might affect oral glucose tolerance test (OGTT) in normal and type 2 diabetic rats. In OGTT, there were no significant differences in glucose responses between acute fructose- and sucrose-administered groups. However, in normal rats, the AUCs of the blood glucose response for the fructose-administered groups tended to be lower than those of the control and sucrose-administered groups. The AUCs of the lower levels fructose- or sucrose-administered groups tended to be smaller than those of higher levels fructose- or sucrose-administered groups. In type 2 diabetic rats, only the AUC of the lowest level of fructose-administered (0.05 g/kg body weight) group was slightly smaller than that of the control group. The AUCs of fructose-administered groups tended to be smaller than those of the sucrose-administered groups, and the AUCs of lower levels fructose-administered groups tended to be smaller than those fed higher levels of fructose. We concluded from this experiment that fructose has tendency to be more effective in blood glucose regulation than sucrose, and moreover, that smaller amount of fructose is preferred to larger amount. Specifically, our experiments indicated that the fructose level of 0.05 g/kg body weight as dietary supplement was the most effective amount for blood glucose regulation from the pool of 0.05 g/kg, 0.1 g/kg and 0.4 g/kg body weights. Therefore, our results suggest the use of fructose as the substitute sweetener for sucrose, which may be beneficial for blood glucose regulation.

Estrogen, Body Weight, and Appetite

  • Bond, Eleanor F.;Deechakawan, Wimon;Chung, Shih-Chi
    • Perspectives in Nursing Science
    • /
    • 제2권1호
    • /
    • pp.92-104
    • /
    • 2005
  • Obesity rates are increasing worldwide, associated with excess acute and chronic disease risk. In most countries, obesity rates among women exceed rates in men, particularly during the post menopausal years. Many factors affect body weight and appetite, including age, metabolic rate, physical activity level, stress, cultural factors, socioeconomic status, health status and health literacy, diet composition, attitudes, and beliefs. Gender affects appetite and body weight indirectly by altering factors contributing to food choice. However, there is emerging evidence that gender affects appetite and body weight directly, altering the physiological control systems regulating appetite. The follicular menstrual cycle phase (estrogen-rich) is associated with relative suppression of appetite. Lower estrogen levels are associated with increased food intake, body weight gain, and altered body fat distribution in humans and animals. This paper reviews the linkages between estrogen and appetite regulation. While relationships among appetite, body weight, and gender-linked hormones are complex, research elucidating these interrelationships could lead to development of gender-specific treatment approaches for obesity and appetite dysregulation.

  • PDF

알루미늄 합금제 어선건조를 위한 선체구조기준 설정에 관한 연구 (A Study on the Standard of Ship Hull Construction for Aluminium Alloys Fishing Boats)

  • 홍봉기
    • 수산해양교육연구
    • /
    • 제12권1호
    • /
    • pp.22-82
    • /
    • 2000
  • The ship hull construction materials of fishing boat has changed in order that wooden, steel, and fiber glass reinforced plastic(FRP). The fishing boat made from FRP has increased every year because that materials has proved excellent of the characteries for fishing boats construction members. Recently, FRP tend towards evasion for the pollution of air enviroment. Therefore. the materials of fishing boat construction must be exchanged by another one. Aluminium alloys must be recommended for fishing boats construction mateials because that is light weight and corrosion resisting in the sea water. Regulation of the standard of ship hull construction for aluminium alloys fishing boats did not enact laws in the interior now. Therefore, this regulation was studied by the following items. that is Rudder, Bottom construction, Side hull plate construction, Deck plate construction, piller. Water tight bulkhead, Deep tank, Fish tank, Stern construction, Superstructure, Deck house construction, Hatch, Engine room opening, Hatch opening, Bulwark, Welding and Rivet etc. A study on the regulation will be contributed to enact laws for fishing boat construction of aluminium alloys.

  • PDF

선박용 갑판크레인의 지브의 경량화설계 (Weight Reduction Design for a JIB of Deck Crane for Shipment)

  • 한동섭;이문재;한근조
    • 대한기계학회논문집A
    • /
    • 제33권4호
    • /
    • pp.396-400
    • /
    • 2009
  • The demand of JIB crane to handle a container or a bulk in a vessel is increasingly because of the growth of the scale of trade through the sea. This deck crane such as JIB crane is required the weight reduction design because it is installed in the deck of a vessel due to the environment regulation. In this study first we carry out the structural analysis of JIB with respect to the luffing angle of it to calculate the maximum equivalent stress of JIB, and next the optimum design for the weight reduction design of JIB. The thickness in a cross section of JIB is adopted as the design variable, the weight of JIB as the objective function, and the von mises stress as the constraint condition for the optimum design of JIB using the ANSYS 10.0.

Evidence for Regulation of Interaction of Endogenous Protein Kinase C(Pkc) Substrates with Plasma Membrane by PKC Down-Regulation in K562 Cells

  • Kim, Young-Sook
    • Archives of Pharmacal Research
    • /
    • 제18권5호
    • /
    • pp.301-307
    • /
    • 1995
  • In the particulate fraction obtained from PKC-down regulated K562 cells by treatment for 24 h with 200nM TPA, phosphorylation of two proteins with molecular weight, 100 kDa and 23 kDa (designated p100 and p23, respectvely) was depleted and addition of exogenous purified PKC to this fraction failed to testore their phosphorylation. However, in the soluble fraction, all of phosphoproteins abolished by long-term treatment with TPA were restored by exogenously added PKC. Phosphorylation of two proteins was increased by short-term tretment (20 min), and diminished with the persistant exposure to TPA as well as at a concentration as low as 1nM. When K562 cells were treated with 1 nM and 200 nM TPA for 24 h, phosphorylation of p100 was restored with or without exogenous PKC on 2-3day and 6day after removal of treated TPA, respectively. Two-dimensional electrophoresis of phosphoproteins revealed that phosphorylated p100 (pl=5.9) and p66 species were completely absent from the particulate fraction of K562 cells treated with 200nM TPA for 24 h. These results suggest that the interaction of sensitive endogenous substrates, p100 and p23 with the plasma membrane might be regulated by PKC-down regulation without displacement to the cytosol and the interaction of p100 with the membrane might be reveersible.

  • PDF

국내 모듈러 건축의 내화구조 제도 현황 및 활성화 방안 (Fire Resistant Regulation Status and Activation Plan of Domestic Modular Construction)

  • 최윤정;안재홍
    • 한국건축시공학회지
    • /
    • 제22권6호
    • /
    • pp.673-680
    • /
    • 2022
  • 모듈러 건축은 시공 기간의 단축, 건축비용 절감 등의 여러 가지 장점에도 불구하고 국내 건설시장에서 좀처럼 탄력을 받지 못하고 있다. 이러한 원인에는 모듈러 내화 기술 적용의 한계도 있으나 무엇보다 내화구조 제도에 대한 접근성이 쉽지 않은 것이 주요 요인으로 간주되고 있다. 따라서 모듈러 건축 활성화를 위해 주요 저해요인인 내화구조 제도 현황과 문제점에 대해 고찰하였으며, 내화구조 제도적 개선 및 연구개발 방향에 대해 제시하고자 한다.

여성 소비자의 식생활 라이프스타일에 따른 체중 조절 행위에 관한 연구 (A Study on Weight Control Behavior by Female Consumers Eating Life Styles)

  • 한인경;하애화
    • 한국식품영양학회지
    • /
    • 제22권2호
    • /
    • pp.177-184
    • /
    • 2009
  • The study investigated the eating lifestyles of female consumers and whether they influenced weight control behavior. The findings of the study can be summarized as follows. First, the eating lifestyles of the subjects were presented four types: 'active eating life pursuit type', 'safe economical type', 'gourmet type' and 'passive negligence type'. In general, most cases were of the 'passive negligence type'. Second, weight control behavior was analyzed according to eating lifestyle. The results of the analysis indicated that the female consumers of the 'active eating life pursuit type' and 'safe economy type' had high behavior levels in each aspect of weight control attitude, subjective regulation, perceived behavior control, and behavior intention. Third, the 'gourmet type', with a strong preference for taste, and the 'passive negligence type', with fewer eating considerations in general, showed weaker attitudes towards weight control and the recognition of pressure from people around them. As such, the level of consideration for food or eating was correlated with weight control. These findings impliedy that the more active, safer, and economical women are in their general eating style, the stronger they perceive weight control issues.

Investigation of single nucleotide polymorphism in TSH-β and CaSR associated with body weight in Korean native chickens (Gray Brown)

  • Oh, Dongyep;Ha, Jae Jung;Yi, Jun Koo;Kim, Dae Hyun;Oh, Seung Min;Kim, Songmi;Han, Kyudong;Park, Yong-Soo
    • 한국동물생명공학회지
    • /
    • 제36권3호
    • /
    • pp.129-136
    • /
    • 2021
  • This study identified single nucleotide polymorphisms (SNPs) that affect the body weight of chickens. Analysis of body weight showed that the Cornish breed had the highest body weight, and the Korean native chicken (Gray Brown) had the lowest body weight. TSH is composed of an α-subunit and a β-subunit, and the TSH-β gene encoding the β-subunit has been reported to be associated with obesity. In chickens, it is located on chromosome 26 and is reported to be associated with growth. The calcium-sensing receptor gene (CaSR) plays a role in the regulation of extracellular calcium homeostasis and is responsible for calcium absorption in the urinary tract, which affects the eggshell quality in poultry. It was shown that TSH-β was strongly correlated with weight in Cornish and Korean native (Gray Brown) chickens, particularly in those with the CC trait. However, CaSR showed no association with body weight in poultry; it was associated with calcium and the eggshell. Thus, selection for TSH-β can be used to produce individuals with more favorable traits in terms of body weight.

자폐증 청소년에서 체중감소와 연관된 반추적 구토의 정신과적 치료 (Psychiatric Treatment of Ruminative Vomiting and the Associated Weight Loss in an Adolescent Boy with Autism : A Case Report)

  • 신윤오;이문성
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
    • /
    • 제20권1호
    • /
    • pp.39-43
    • /
    • 2009
  • We treated the persistent ruminative vomiting of a 13-year-old autistic boy by using a behavioral and psychopharmacological approach in a closed ward. Before the interventions, the patient had lost about 10kg of body weight due to very high-frequency ruminative vomiting. Together with psychopharmacological trials, the psychiatric treatment included a combination of a behavioral approach and food regulation that emphasized food restrictions, and we provided regular light meals. There was a considerable reduction of the ruminative vomiting and 2kg weight gain was achieved during the admission. These therapeutic gains were maintained at the 4-month follow-up assessment and the vomiting symptom reached a near-zero level and the weight loss were recovered by about 8kg. The issues related to the treatment approaches for ruminative vomiting with autism are discussed.

  • PDF